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2,3-Bis(amino((2-aminophenyl)thio)methylene)succinonitrile+compou
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2,3-Bis(amino((2-aminophenyl)thio)methylene)succinonitrile+compou
Catalog Number:
(10669-744)
Supplier:
Bioss
Description:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF23 (RING finger protein 23), also known as tripartite motif-containing protein 39 (TRIM39) or testis-abundant finger protein, is a 518 amino acid protein belonging to the TRIM/RBCC family that is known to interact with MOAP1. Ubiquitously expressed and existing as two alternatively spliced isoforms, RNF23 is found at highest levels in spleen, testis, brain, kidney, liver, heart and skeletal muscle. RNF23 typically localizes to cytosol but shifts to mitochondria upon co-localization with MOAP1, a short-lived, pro-apoptotic protein which RNF23 prevents from becoming poly-ubiquitinated and degraded, thereby facilitating apoptosis. RNF23 contains one B box-type zinc finger, a B30.2/SPRY domain and a single RING-type zinc finger.
Catalog Number:
(10763-298)
Supplier:
Biolegend
Description:
Purified anti-Histone H3 Phospho (Ser28) (MaxPar® Ready) [HTA28]; Isotype: Rat IgG2a, κ; Reactivity: Human; Apps: WB, CyTOF®; Size: 100 μg
Supplier:
Adipogen
Description:
Suitable for the fluorimetric detection of Zn2+ (after esterase hydrolysis). Spectral data: lambdaex 492nm; lambdaem 515nm in PBS.
Supplier:
ALADDIN SCIENTIFIC
Description:
4'-Aminoacetophenone hydrochloride ≥98%
Catalog Number:
(103528-178)
Supplier:
Acros Organics
Description:
Dichloromethane, stabilized with amylene, Purity: 99+%, Extra pure, Cas number: 75-09-2, Molecular Weight: 84.93, Molecular formula: C H2 Cl2, form: Liquid, Color: Colorless, Synonyms: Methylene chloride, Size: 5L
Supplier:
AMBEED, INC
Description:
(4S,4aR,5S,5aR,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride ≥98%
Supplier:
AMBEED, INC
Description:
5-(4-propoxybenzylidene)thiazolidine-2,4-dione, Purity: 98%, CAS Number: 587852-28-6, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 10mg
Catalog Number:
(MK4874-26)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Methylene Chloride Nf 200L
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2-Aminophenylboronic acid pinacol ester 97%
Supplier:
AMBEED, INC
Description:
4-(2-Propynyloxy)aniline 98%, Ambeed.Inc
Supplier:
Enzo Life Sciences
Description:
HDAC1 inhibitor
Catalog Number:
(75788-808)
Supplier:
Prosci
Description:
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. Human IL-31 cDNA encodes a 164 amino acid precursor that contains a 23 amino acid signal peptide and a 141 amino acid mature protein. Human and mouse IL-31 share 24% sequence identity in the mature region. IL-31 is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2). IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM R beta ). The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN gamma on monocytes. GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Studies have shown that IL31 induces severe pruritis (itching) and dermatitis in transgenic mice.
Supplier:
AMBEED, INC
Description:
N-((2-Hydroxynaphthalen-1-yl)methylene)thiophene-2-sulfonamide, Purity: 98%, CAS Number: 307543-71-1, Appearance: Form: solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 10mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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