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Catalog Number:
(76110-348)
Supplier:
Bioss
Description:
The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26; Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044219-5G , MDL Number: MFCD08689663
Catalog Number:
(10797-498)
Supplier:
Prosci
Description:
Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 R?1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13R?1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Catalog Number:
(10670-466)
Supplier:
Bioss
Description:
The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26; Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.
Catalog Number:
(10670-462)
Supplier:
Bioss
Description:
The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26; Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.
Catalog Number:
(75835-366)
Supplier:
Restek
Description:
Calibration standard Amine 900 Test Mix, 8 components, Concentration: In methanol:methylene chloride (50:50), Storage: 0 deg C or colder, Shelf Life: 1 months, Volume: 1 mL/ampule
Supplier:
TCI America
Description:
CAS Number: 104376-79-6
MDL Number: MFCD00941454 Molecular Formula: C18H18N8O7S3 Molecular Weight: 598.53 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 236 Specific rotation [a]20/D: -160 deg (C=1, H2O)
Catalog Number:
(75835-800)
Supplier:
Restek
Description:
Standard Benzidines Mix 8270, Concentration: 2000ug/mL each in methylene chloride, Components: Benzidine (92-87-5), 3,3'-Dichlorobenzidine (91-94-1), 3,3'-Dimethylbenzidine (o-tolidine) (119-93-7), Minimum shelf life: 6 months, Volume: 1mL/ampul
Catalog Number:
(75835-802)
Supplier:
Restek
Description:
Standard 1,4-Dioxane, CAS number: 123-91-1, Concentration: 2,000 ug/mL in methylene chloride, SV stock, Molecular formula: CH2CL2, Minimum shelf life: 6 months, Volume: 1 mL/ampul
Supplier:
Diagnostic Biosystems
Description:
Complement 4d (C4D) is the most clinically used marker for humoral rejection. It is a degradation product of the activated complement factor C4B. Complement 4D is typically initiated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. Complement 4D is also found in intracytoplasmic vacuoles of endothelial cells. Covalent binding renders C4D a stable molecule that can easily be detected by immunohistochemistry.
Supplier:
MilliporeSigma
Description:
Clear and free from particulates. Suitable for use in organic synthesis and other anhydrous solvent applications.
Elbow adapter with septum cap (EM-692004-2) allows for the removal of solvent under nitrogen atmosphere. Replacement septum (EM-692004S-2), for use with elbow adapters, minimizes air and moisture intrusion once the primary septum is punctured. Drying tube (EM-692010-2) filled with t.h.e.* desiccant indicating silica gel removes solvent under a dry-air atmosphere. Large plug (EM-692012-2) is a replacement plug for bottle top.
Catalog Number:
(EM1.06454.1000)
Supplier:
MilliporeSigma
Description:
Suprasolv® hypergrade is a unique and universal solvent quality which can be employed for all three GC detection methods (ECD, FID and MS). Thanks to the large retention time range, even low-boiling substances can be reliably analyzed.
Supplier:
Adipogen
Description:
Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Blocks class I, class II and class III PI3Ks, including some downstream targets. Blocks class I PI3K persistently and class III PI3K transiently. Induces autophagy under nutrient-rich conditions and inhibits starvation-induced autophagy due to differential effects on class I versus class III PI3 kinase. Shows some limited Vps34 preference in vitro compared to PtdIns3Kgamma. However, it is typically employed in cellular studies at a concentration of 10 mM, which can inhibit all PtdIns3Ks. Can target other kinases and affect other cellular processes, such as glycogen metabolism, lysosomal acidification, endocytosis and mitochondrial permeability transition. Anticancer compound. Neuroprotective. PKA-activation dependent lipolytic agent. Enhances ATGL-dependent hydrolysis of triacylglycerols.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044462-1G , MDL Number: MFCD00664271
Catalog Number:
(80058-532)
Supplier:
MilliporeSigma
Description:
(OSGP). White solid. HYGROSCOPIC. Non-ionic detergent that has been used to isolate membrane proteins from E. coli without inactivation. Stable in aqueous solution and easily removed by dialysis.
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