3-(4-Propoxyphenoxy)azetidine
Catalog Number:
(10397-334)
Supplier:
Bioss
Description:
Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.
Catalog Number:
(10468-702)
Supplier:
Bioss
Description:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.
Catalog Number:
(10342-586)
Supplier:
Bioss
Description:
Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Catalog Number:
(10461-486)
Supplier:
Bioss
Description:
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Catalog Number:
(10423-334)
Supplier:
Bioss
Description:
Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
Catalog Number:
(10392-290)
Supplier:
Bioss
Description:
DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. It contains three His containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It has sphingolipid-delta-4-desaturase activity and converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).
Catalog Number:
(10470-006)
Supplier:
Bioss
Description:
The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
Catalog Number:
(10422-872)
Supplier:
Bioss
Description:
In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.
Catalog Number:
(10451-258)
Supplier:
Bioss
Description:
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
Catalog Number:
(10478-266)
Supplier:
Bioss
Description:
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.
Catalog Number:
(10237-494)
Supplier:
Bioss
Description:
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
Catalog Number:
(10280-872)
Supplier:
Bioss
Description:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Catalog Number:
(10240-770)
Supplier:
Bioss
Description:
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
Catalog Number:
(103369-022)
Supplier:
Novus Biologicals
Description:
The BMAL1 Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to BMAL1. This antibody reacts with human, mouse, rat, primate. The BMAL1 Antibody [FITC] has been validated for the following applications: Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Catalog Number:
(10303-386)
Supplier:
Bioss
Description:
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Catalog Number:
(103293-050)
Supplier:
Novus Biologicals
Description:
The Mas Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to Mas. This antibody reacts with human, mouse, rat. The Mas Antibody [FITC] has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
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