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2,4-Difluoro-3-(methylthio)benzoic+acid
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2,4-Difluoro-3-(methylthio)benzoic+acid
Supplier:
AOB CHEM USA
Description:
Methyl 3,4-difluoro-2-methoxybenzoate ≥97%
Supplier:
AOB CHEM USA
Description:
1-(2,3-Difluoro-4-methylphenyl)-1-propanone ≥95%
Supplier:
AOB CHEM USA
Description:
5-(Cyclopropylmethoxy)-1,3-difluoro-2-iodobenzene ≥95%
Catalog Number:
(103007-314)
Supplier:
Anaspec Inc
Description:
Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.
This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2,4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm. Sequence:Abz-HPGGPQ-EDDnp MW:920 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(102552-808)
Supplier:
BioVendor
Description:
Human Lecithin: cholesterol acyltransferase (LCAT) is a glycoprotein with a molecular mass of approximately 58 kDa. It is the key enzyme responsible for esterification of free cholesterol to cholesteryl esters in circulating plasma lipoproteins, primarily in high density lipoprotein (HDL). The tertiary structure of LCAT is maintained by two disulfide bridges, similar to lipases and other proteins of the α/β hydrolase fold family. Mature LCAT protein is synthesized from a 440 residue precursor by following cleavage of a 24 residue signal peptide. The mature protein contains 416 amino acids and is heavily N-glycosylated. LCAT is abundant in blood plasma and it is present in other organs, including liver, brain and testes. In plasma LCAT is associated with ApoD which frequently co-purify.
Supplier:
AOB CHEM USA
Description:
3,4-Difluoro-2-methylbenzaldehyde ≥97% research grade
Catalog Number:
(AAH63030-06)
Supplier:
Thermo Scientific Chemicals
Description:
4, 5-Difluoro-2-nitrotoluene, Purity: 98%, CAS Number: 127371-50-0, molecular formula: C7H5F2NO2, color: Colorless to pale, Form: Liquid, Synonyms: 1, 2-Difluoro-4-methyl-5-nitrobenzene, 5g
Supplier:
AOB CHEM USA
Description:
2,6-Difluoro-3-methylbenzaldehyde ≥97%
Supplier:
AOB CHEM USA
Description:
2,6-Difluoro-4-methoxybenzonitrile ≥95%
Supplier:
AMBEED, INC
Description:
2,6-Difluoro-4-methoxybenzaldehyde, Purity: 98%, CAS Number: 256417-10-4, Appearance: White to yellow or pale-red powder or crystals, Storage: Inert atmosphere, 2-8 C, Size: 10g
Supplier:
AOB CHEM USA
Description:
1-(2,6-Difluoro-3-iodophenyl)propan-1-one ≥95%
Catalog Number:
(75789-550)
Supplier:
Prosci
Description:
Lysosomal Associated Membrane Protein 2 (LAMP2) is a major component of lysosomal membranes. LAMP2 is a transmembrane glycoprotein about 110kDa. Mature human LAMP2 consists of a 347 amino acid (aa) intralumenal domain, a 24 aa transmembrane segment, and a 35 aa cytoplasmic tail . The lumenal domain is organized into two heavily N-glycosylated regions. Alternate splicing generates a human LAMP2 isoform (LAMP2B) with a substituted juxtamembrane lumenal region, cytoplasmic tail and transmenmbrane segment.LAMP2 itself can cleavage lysosomal luminal domain and degradation lysosomal. In the help of chaperone HSC73,LAMP2 mediates the lysosomal uptake in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles.
Catalog Number:
(10073-162)
Supplier:
Prosci
Description:
4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13 kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24 kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Supplier:
AOB CHEM USA
Description:
Methyl 2,3-difluoro-4-methyl-α-oxobenzeneacetate ≥95%
Catalog Number:
(76195-990)
Supplier:
Prosci
Description:
Recognizes a protein of 16-27kDa, identified as human Interferon alpha 2 (IFNA2). Its epitope maps between amino acids 43-53 of the IFNA2. This mAb is specific for IFNA2 and does not cross-react with IFNA1. The epitopes of clones N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFNA2 after viral infections. The IFNA family consists of 24 or more genes or pseudo-genes. The alpha interferons are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
Supplier:
AOB CHEM USA
Description:
(4-Chloro-2,3-difluoro-5-methoxyphenyl)(methyl)sulfane 97
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This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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