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Supplier:  Adipogen
Description:   ZSTK474 Inhibits all four PI3K isoforms in an ATP-competitive manner. IC(50) is approximately 37nM.
Catalog Number: (101095-254)

Supplier:  USP
Description:   (1 mL)
Supplier:  Bachem Americas
Description:   Sequence: H-α-Difluoro-Me-DL-Orn-OH · HCl · Hâ‚‚O
Synonym(s): Eflornithine · HCl · H₂O#DFMO · HCl · H₂O#α-Difluoromethylornithine · HCl · H₂O
Supplier:  Adipogen
Description:   Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has been found to limit migration of human fibrosarcoma cells. Thus, the inhibition of LIMK1 and/or LIMK2 enzymes have been suggested as targets for treating cancer, including reduction or prevention of metastasis. BMS-5 is a potent inhibitor of the LIM kinase. It has IC(50) values of 7nM and 8nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate and the kinase domains of LIMK1 and LIMK2 as the enzyme sources in the presence of 1µM ATP.
Catalog Number: (TS46270-0250)

Supplier:  THERMO FISHER SCIENTIFIC CHEMICALS
Description:   Eflornithine hydrochloride monohydrate
Supplier:  Matrix Scientific
Description:   MF=C3Hcl2F5O MW=218.94 Cas=32778-07-7 MDL=MFCD01320775 ,25G
Supplier:  AMBEED, INC
Description:   Benzofuran-5-sulfonyl chloride 95%
Supplier:  APOLLO SCIENTIFIC
Description:   Pyridine-3-sulfonyl chloride 98%
Supplier:  AMBEED, INC
Description:   Piperidine-1-sulfonyl chloride 95%

Supplier:  AMBEED, INC
Description:   2-Cyano-4-methylbenzene-1-sulfonyl chloride ≥98%
New Product
Supplier:  Thermo Scientific Chemicals
Description:   Piperidine-1-sulfonyl chloride, Purity: 97%, Cas no. 35856-62-3, Molecular formula: C5H10ClNO2s, Form: Liquid, Color: Red, size: 5G
MSDS SDS
Supplier:  AMBEED, INC
Description:   1-Allylcyclopropane-1-sulfonyl chloride, Purity: 97%, CAS Number: 923032-59-1, Appearance: Colorless to Yellow Liquid, Storage: Inert atmosphere, 2-8 C, Size: 5g
Supplier:  AMBEED, INC
Description:   6-Methylpyridine-3-sulfonyl chloride, Purity: 95%, CAS Number: 478264-00-5, Appearance: Solid or liquid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Supplier:  Matrix Scientific
Description:   [(4-Fluorophenyl)sulfonyl]acetonitrile ≥97%

Supplier:  AMBEED, INC
Description:   1,3-benzodioxole-5-sulfonyl chloride ≥98%
New Product
Supplier:  Matrix Scientific
Description:   3',4'-Dichlorobiphenyl-4-sulfonyl chloride ≥97%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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