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2-(1-Methylguanidino)ethyl+dihydrogen+phosphate
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2-(1-Methylguanidino)ethyl+dihydrogen+phosphate
Catalog Number:
(75793-728)
Supplier:
Prosci
Description:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
Catalog Number:
(76079-856)
Supplier:
Bioss
Description:
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Catalog Number:
(77439-710)
Supplier:
Bioss
Description:
IGRP (islet specific glucose 6 phosphatase catalytic subunit related protein), also known as G6PC2, belongs to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyses the hydrolysis of glucose-6-phosphate. This hydrolysis is the terminal step in gluconeogenic and glycogenolytic pathways, and allows the release of glucose into the bloodstream. IGRP is found in pancreatic islets and does not exhibit phosphohydrolase activity. However, it is a major target of cell-mediated autoimmunity in diabetes.
Catalog Number:
(89350-830)
Supplier:
Genetex
Description:
Calcitonin is a peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone.
Catalog Number:
(76422-512)
Supplier:
Biolegend
Description:
CD123, Monoclonal Antibody, Clone: S18016C, Host: Mouse, Species Reactivity: Human, Isotype: IgG1, K, Immunogen: Hu CD123 transfectants, Other Names: IL-3RA, IL-3 Receptor alpha, Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, Size: 100 uG
Catalog Number:
(10105-546)
Supplier:
Prosci
Description:
SATB1 binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. SATB1 was thought to recognize the sugar-phosphate structure of double-stranded DNA.
Supplier:
MilliporeSigma
Description:
Sputolysin reagent is a concentrate of dithiothreitol (DTT) in phosphate buffer intended for isolation of epithelial cells, pathogenic or saprophytic bacteria, fungi and yeasts from sputum.
Catalog Number:
(76422-244)
Supplier:
Biolegend
Description:
CD3 Monoclonal Antibody, host: Mouse, Clone: SK7, Reactivity: Human, Isotype: IgG1, K, Conjugate: PerCP/Cyanine5.5, Formulation: Phosphate-buffered solution, Storage: should be stored undiluted between 2deg C and 8deg C and, Application: FC, Synonyms: T3, CD3E, Size: 500 uL
Catalog Number:
(77438-252)
Supplier:
Bioss
Description:
Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A.
Catalog Number:
(10392-376)
Supplier:
Bioss
Description:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
Catalog Number:
(10665-800)
Supplier:
Bioss
Description:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
Catalog Number:
(89269-662)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to SLC25A24 (N-terminal)
Supplier:
Adipogen
Description:
Tamatinib effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals.
Catalog Number:
(101410-694)
Supplier:
Electron Microscopy Sciences
Description:
Stabilized, Reagent, A.C.S. H2O2 Â F.W. 34.01 Â CAS #7722-84-1 Assay 29-32% Maximum of Impurities: Chloride(Cl) 0.000003 Nitrate 0.000002 Phosphate 0.000002 Sulfate 0.000005 Heavy Metal 0.000001 Iron 0.0000005 Titratable Acid
Catalog Number:
(10391-064)
Supplier:
Bioss
Description:
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Catalog Number:
(10353-060)
Supplier:
Bioss
Description:
Inhibitor of protein-phosphatase 1.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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