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2-(1-Methylguanidino)ethyl+dihydrogen+phosphate


26,971  results were found

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Supplier:  AVANTOR PERFORMANCE MATERIALS US
Description:   Ethyl acetate ≥99% NF, J.T.Baker®
MSDS SDS
Supplier:  Bioss
Description:   Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RNA hybrids, single-stranded DNA regions of R-loop structures, and single-stranded RNA molecules. Has a 3'-5' exoribonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapped DNA molecules during short-patch BER. Possesses a DNA 3' phosphodiesterase activity capable of removing lesions (such as phosphoglycolate) blocking the 3' side of DNA strand breaks. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Acts as a loading factor for POLB onto non-incised AP sites in DNA and stimulates the 5'-terminal deoxyribose 5'-phosphate (dRp) excision activity of POLB. Plays a role in the protection from granzymes-mediated cellular repair leading to cell death. Also involved in the DNA cleavage step of class switch recombination (CSR). On the other hand, APEX1 also exerts reversible nuclear redox activity to regulate DNA binding affinity and transcriptional activity of transcriptional factors by controlling the redox status of their DNA-binding domain, such as the FOS/JUN AP-1 complex after exposure to IR. Involved in calcium-dependent down-regulation of parathyroid hormone (PTH) expression by binding to negative calcium response elements (nCaREs).
Catalog Number: (89269-654)

Supplier:  Genetex
Description:   Rabbit polyclonal antibody to GPD2 (N-terminal)

Supplier:  Prosci
Description:   Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
Supplier:  ANTIBODIES.COM LLC
Description:   Rabbit polyclonal antibody to PFK-1 for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Catalog Number: (89269-652)

Supplier:  Genetex
Description:   Rabbit polyclonal antibody to GPD2 (Middle)
Catalog Number: (89270-596)

Supplier:  Genetex
Description:   Rabbit polyclonal antibody to RTCD1 (N-terminal)
Supplier:  Biolegend
Description:   PerCP/Cy5.5 anti-mouse/rat XCR1 [ZET]; Isotype: Mouse IgG2b, κ; Reactivity: Mouse, Rat; Apps: FC; Size: 100 μg
Catalog Number: (89366-424)

Supplier:  Genetex
Description:   Rabbit polyclonal to Sphingolipid Receptor Edg3/S1P3
Catalog Number: (89298-046)

Supplier:  Genetex
Description:   Goat polyclonal antibody to GAPDH (C Terminus)
Catalog Number: (89366-420)

Supplier:  Genetex
Description:   Rabbit polyclonal to Sphingolipid Receptor Edg1/S1P1

Supplier:  MP Biomedicals
Description:   Product is the lyophilized powder of goat antiserum to human serum and buffer salts.
The antiserum is prepared by immunizing goats with human serum; antiserum is delipidated and made specific by
immunoadsorption with soluble antigens or solid-phase immunoadsorption where appropriate. The resulting antiserum is
dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, with 0.05% sodium azide, adjusted to standard titer,
filtered through a 0.22 µm filter, vialed and lyophilized
Supplier:  Biolegend
Description:   Purified anti-mouse FcεRIα (MaxPar® Ready) [MAR-1]; Isotype: Armenian Hamster IgG; Reactivity: Mouse; Apps: FC, CyTOF®; Size: 100 μg

Supplier:  Bioss
Description:   Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Supplier:  Bioss
Description:   Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.

Supplier:  Bioss
Description:   Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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