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2-(2-Methyl-1-piperidinyl)isonicotinic+acid
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2-(2-Methyl-1-piperidinyl)isonicotinic+acid
Catalog Number:
(10667-364)
Supplier:
Bioss
Description:
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
Catalog Number:
(10667-358)
Supplier:
Bioss
Description:
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
Supplier:
TCI America
Description:
CAS Number: 542-55-2
MDL Number: MFCD00003293 Molecular Formula: C5H10O2 Molecular Weight: 102.13 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 98 Flash Point (°C): 10 Specific Gravity (20/20): 0.89
Catalog Number:
(77439-950)
Supplier:
Bioss
Description:
The GCLC gene consists of 16 exons and encodes the 636 amino acid protein g-GCSc (g-glutamylcysteine synthetase heavy subunit), also designated g-L-glutamate-L-cysteine ligase catalytic subunit (GLCLC). g-GCSc is expressed in hemocytes, brain, liver and kidney. g-GCSc associates with a regulatory or modifier subunit, g-GCSm (g-glutamylcysteine synthetase light subunit), to form a heterodimer, g-GCS. g-GCS is the first enzyme involved and the rate determining step in glutathione biosynthesis. Oxidants, cadium and methyl mercury upregulate the transcription of g-GCS. H2O2 regulation depends on the Yap1 protein and the presence of glutamate, glutamine and lysine. Cadium regulates transcription through proteins Met-4, Met-31 and Met-32. Cbf1, a DNA binding protein, inhibits transcription of g-GCS. Chemopreventive compounds cause increased levels of g-GCSc in kidney tissues, which may protect against chemically induced carcinogenesis. A His370Leu amino acid change in g-GCSc causes deficiencies in activity which are responsible for hemolytic anemia and low red blood cell glutathione levels. Defects in GCLC are the cause of hemolytic anemia.
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 1736-21-6, MDL: MFCD03407356
Supplier:
MERCK, S.A. DE C.V. SV
Description:
Offering a high degree of UV transmittance, low particle count, low acidity and alkalinity, and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. They are produced from specially selected raw materials, and undergo a number of purification steps prior to final packaging. Since separations are normally carried out under gradient conditions in analytical HPLC, Merck Millipore offer solvents in ’gradient grade’ as well as ’isocratic grade’. This enables you to minimise the gradient effect of the solvent involved.
Catalog Number:
(102988-950)
Supplier:
Adipogen
Description:
Resorcylic acid lactone. Mycotoxin. Regulator of fungal morphogenesis. Mycoestrogen with anabolic and uterotrophic activity. Ecdysteroid antagonist. Gonadotropin inhibitor. Interleukin antagonist. Apoptosis inducer. Analytical standard in food industry.
Catalog Number:
(76009-558)
Supplier:
Prosci
Description:
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Supplier:
MP Biomedicals
Description:
Choline chloride is an organic compound and a quaternary ammonium salt. It is a weak acid. Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. Choline chloride is a common food additive in animal husbandry
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes. Choline chloride is used as a source of methyl groups for methyl-transfer reactions. Physical Appearance: Hard, White Crystalline Powder pH: Neutral to Litmus Vapor Pressure: 10 hPa at 20 °C (Lit.) Partition Coefficient: n octanol/water (logKow): -3.77 at 25 °C (lit.) Solubility: Soluble in water: (10% aq soln) Clear, Colorless Solution
Catalog Number:
(76009-778)
Supplier:
Prosci
Description:
Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.
Catalog Number:
(75933-790)
Supplier:
Rockland Immunochemical
Description:
Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints; targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3).
Supplier:
AMBEED, INC
Description:
2-Aminoethyl methacrylate hydrochloride, Purity: 90% contains approx 500 ppm phenothiazine as stabilizer, CAS Number: 2420-94-2, Appearance: Form: solid, Storage: Inert atmosphere, 2-8 C, Size: 250mg
Catalog Number:
(PI20278)
Supplier:
Invitrogen
Description:
Thermo Scientific Pierce Coomassie Brilliant Blue R-250 is one of the most common forms of coomassie dye, which is a key component of various colorimetric protein gel stains.
Supplier:
TCI America
Description:
CAS Number: 28460-01-7
MDL Number: MFCD00015131 Molecular Formula: C6H15O3PS Molecular Weight: 198.22 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 120 Flash Point (°C): 101 Specific Gravity (20/20): 1.14
Supplier:
Thermo Scientific Chemicals
Description:
Applications: Polyaniline is used in chemical vapor sensors, supercapacitors and biosensors. It is also useful for manufacture of electrical conducting yarns, antistatic coatings, electromagnetic shielding, flexible electrodes and printed circuit board. Further, it is used in antistatic and ESD coatings and corrosion protection.
Supplier:
Restek
Description:
MXT®-WAX columns are good for general-purpose applications involving FAMEs, flavor compounds, essential oils, amines, solvents, xylene isomers, and U.S.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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