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2-(2-Methylphenyl)ethanol
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2-(2-Methylphenyl)ethanol
Supplier:
MP Biomedicals
Description:
Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. 
Supplier:
TCI America
Description:
4-Ethoxy-2-methylphenylboronic Acid (contains varying amounts of Anhydride), CAS: 313545-31-2, Molecular Formula: C9H13BO3, MW: 180.01, Synonym: 4-Ethoxy-2-methylbenzeneboronic Acid (contains varying amounts of Anhydride), Form: Crystal- Powder, Size: 1G
Catalog Number:
(101094-230)
Catalog Number:
(100503-730)
Supplier:
Electron Microscopy Sciences
Description:
(Butyl Cellosolve®; Ethylene Glycol Monobutyl Ether) CH3(CH2)3OCH2CH2OH F.W. 118.18 CAS 111-76-2 Specific Gravity: 0.90 b.p. 169°C.
Supplier:
Adipogen
Description:
Phytotoxin. Derivative of HDAC inhibitor chlamydocin Similar chemical structure to the TAN-1746 compounds (potent HDAC inhibitors).
Supplier:
Matrix Scientific
Description:
MF=C15H13NO2S MW=271.34 CAS=36635-66-2 MDL=MFCD04114776 1G
Catalog Number:
(77686-518)
Supplier:
AMBEED, INC
Description:
3-Chloro-4-fluoro-5-methylphenylboronic acid, pinacol ester ≥98%
Supplier:
Enzo Life Sciences
Description:
Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2a) (IC50=2µM) and SAPK2b (p38β) (IC50=2µM). Induces a paradoxical >100-fold activation of c-Raf in whole cells.
Catalog Number:
(10108-634)
Supplier:
Prosci
Description:
ADH6 is class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
Catalog Number:
(TCT0791-10G)
Supplier:
TCI America
Description:
CAS Number: 433-27-2
MDL Number: MFCD00000441 Molecular Formula: C4H7F3O2 Molecular Weight: 144.09 Purity/Analysis Method: >80.0% (GC) Form: Clear Liquid Color: Colorless Flash Point (°C): 39 Specific Gravity (20/20): 1.23
Catalog Number:
(TCT1997-5G)
Supplier:
TCI America
Description:
CAS Number: 86259-87-2
MDL Number: MFCD06797175 Molecular Formula: C15H24O5 Molecular Weight: 284.35 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Color: Very Pale Yellow Specific Gravity (20/20): 1.10
Supplier:
TCI America
Description:
CAS Number: 42906-19-4
MDL Number: MFCD03093257 Molecular Formula: C21H19NO Molecular Weight: 301.39 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 109
Catalog Number:
(TCF0955-1G)
Supplier:
TCI America
Description:
3-Fluoro-2-methylphenylboronic Acid (contains varying amounts of Anhydride), CAS Number: 163517-61-1, Molecular Formula: C7H8BFO2, MW: 153.95, Synonym: 3-Fluoro-2-methylbenzeneboronic Acid, 3-Fluoro-o-tolylboronic Acid, Form: Crystal- Powder, Size: 1G
Supplier:
Thermo Scientific Chemicals
Description:
Transition interval (acid): pH 1.8 (orange) to pH 2.0 (yellow); (alkaline) pH 7.0 (yellow) to pH 8.8 (violet)
Supplier:
AOB CHEM USA
Description:
3-Chloro-4-fluoro-5-methylphenylboronic acid, pinacol ester ≥97%
Supplier:
MP Biomedicals
Description:
Trimethoprim is an antibacterial agent; a specific inhibitor of formylation; a dihydrofolate reductase inhibitor.
Trimethoprim is primarily used as an antibacterial agent. It has dihydrofolate reductase inhibitor activity with selectivity for the prokaryote enzyme. It is used to treat urinary tract infections, mild acute prostatitis, recurrent cystitis, asymptomatic bacteriuria during pregnancy and respiratory tract infections. The combination of trimethoprim and sulfamethoxazole interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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