Potassium+tetracyanoplatinate(II)+hydrate
Supplier:
TCI America
Description:
CAS Number: 87-67-2
MDL Number: MFCD00036332 Molecular Formula: C9H19NO7 Molecular Weight: 253.25 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 150 Specific rotation [a]20/D: 17 deg (C=10, H2O)
Catalog Number:
(10061-774)
Supplier:
Prosci
Description:
GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
Supplier:
TCI America
Description:
CAS Number: 104-10-9
MDL Number: MFCD00007922 Molecular Formula: C8H11NO Molecular Weight: 137.18 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 255 Melting point (°C): 108
Catalog Number:
(89158-360)
Supplier:
Enzo Life Sciences
Description:
Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
Catalog Number:
(10751-830)
Supplier:
Prosci
Description:
GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
Catalog Number:
(AAJ60111-AK)
Supplier:
Thermo Scientific Chemicals
Description:
HEPES, 1.0M buffer soln., pH 6.5, sterile-filtered
Catalog Number:
(10748-730)
Supplier:
Prosci
Description:
BICD1 Antibody: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
Catalog Number:
(76009-924)
Supplier:
Prosci
Description:
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Supplier:
AMBEED, INC
Description:
Isopropyl ethanesulfonate 97%
Supplier:
AMBEED, INC
Description:
Sodium 2-(acetylthio)ethanesulfonate, Purity: 97%, CAS Number: 76274-71-0, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 250MG
Supplier:
Adipogen
Description:
The BCR-ABL oncogene triggers intracellular signaling, activating multiple transduction cascades, promoting the growth, proliferation and survival of hematopoietic cells. BCR-ABL plays a role in defective DNA repair, alteration of cellular adhesion and inhibition of apoptosis. Degregulated BCR-ABL tyrosine kinase activity is the molecular marker for CML. Inhibiting BCR-ABL tyrosine kinase activity leads to the induction of apoptosis and inhibits cellular proliferation in vitro and there are various BCR-ABL isoforms with differing activity levels as well. Dasatinib (BMS-354825, Sprycel®) is a potent multi-target kinase inhibitor of BCR-ABL. Dasatiinib performs better against ABL kinase than earlier drugs such as imatinib, and Dasatinib also is effective against SRC family of kinases, and other receptor kinases such as EPHA2, PDGFR, and c-Kit. Dasatinib's inhibiting potential against Src family kinase members is greater (IC(50) 0.5nM) than its inhibitory activity against ABL (1nM).
Catalog Number:
(75928-220)
Supplier:
Rockland Immunochemical
Description:
The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
Catalog Number:
(TCA0906-001G)
Supplier:
TCI America
Description:
CAS Number: 108341-18-0
MDL Number: MFCD00036384 Molecular Formula: C8H11NO3 Molecular Weight: 319.27 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 129 Specific rotation [a]20/D: -11 deg (C=5, H2O)
Supplier:
AMBEED, INC
Description:
2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
Supplier:
AMBEED, INC
Description:
4-[N,N-Bis(4-bromophenyl)amino]benzaldehyde 95%, Ambeed.Inc
Supplier:
BeanTown Chemical
Description:
CAS: 145100-51-2; EC No: 000-000-0; MDL No: MFCD00191833
Crystalline; Molecular Formula: C7H3ClF6N2O4S2; MW: 392.68
Melting Point: 45-47°
Moisture Sensitive
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