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2,5-Dibromo-3-(Dibromomethyl)pyridine
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2,5-Dibromo-3-(Dibromomethyl)pyridine
Supplier:
MP Biomedicals
Description:
Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 046902-1G , MDL Number: MFCD09817444
Supplier:
Matrix Scientific
Description:
MF=C10H12FN5O4 MW=285.24 CAS=21679-14-1 MDL=MFCD00132942 250MG
Catalog Number:
(101797-050)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 009414-1G , MDL Number: MFCD01319213
Catalog Number:
(101822-644)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 026675-500MG , MDL Number: MFCD03773330
Supplier:
AMBEED, INC
Description:
N-(tert-Butoxycarbonyl)-3-(1-naphthyl)-D-alanine 97%
Supplier:
AMBEED, INC
Description:
Gemcitabine 98%
Supplier:
AMBEED, INC
Description:
Calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate, Purity: 98%, CAS number: 147098-20-2, Appearance: Form: Crystal - Powder / Colour: White - Pale-yellow, Storage: Inert atmosphere, Store in freezer, under -20C, Size: 10MG
Supplier:
AMBEED, INC
Description:
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate, disodium salt, Purity: 89%, CAS Number: 56001-37-7, Appearance: White to off-white powder or crystals, Storage: Inert atmosphere, Store in freezer, under -20C, Size: 1G
Supplier:
AMBEED, INC
Description:
(((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid, trisodium salt, Purity: 98%, CAS Number: 36051-31-7, Appearance: White to off-white powder or crystals, Storage: Inert atmosphere, Store in freezer, under -20C, Size: 250MG
Supplier:
Bachem Americas
Description:
Sequence: Fmoc-tBu-Gly-OH
Catalog Number:
(TCA2900-1G)
Supplier:
TCI America
Description:
2-Aminopyrimidine-5-boronic Acid (contains varying amounts of Anhydride), CAS Number: 936250-22-5, Molecular Formula: C4H6BN3O2, Molecular Weight: 138.92, Color: White - Pale yellowWhite - Pale reddish yellow, Size: 1G
Supplier:
AMBEED, INC
Description:
6-Chloro-L-Tryptophan 98%
Supplier:
Adipogen
Description:
AS703026 is a novel, selective, non-competitive, orally bioavailable MEK1/2 inhibitor with experimental IC(50) values of 5-11nM. In use on multiple myeloma cells (MM), AS703026 inhibited growth and survival of MM cells and cytokine-induced osteoclast differentiation more potently (~10X) than AZD6244. Inhibition of proliferation induced by AS703026 was mediated by G0-G1 cell cycle arrest and was accompanied by reduction of MAF oncogene expression. AS703026 further induced apoptosis via caspase 3 and Poly ADP ribose polymerase (PARP) cleavage in MM cells, both in the presence or absence of bone marrow stromal cells (BMSCs). Importantly, AS703026 sensitized MM cells to a broad spectrum of conventional (dexamethasone, melphalan), novel or emerging (lenalidomide, perifosine, bortezomib, rapamycin) anti-MM therapies. Significant tumour growth reduction in AS703026- vs. vehicle-treated mice bearing H929 MM xenograft tumours correlated with downregulated pERK1/2, induced PARP cleavage, and decreased microvessels in vivo. Moreover, AS703026 (<lt/>200nM) was cytotoxic against the majority of tumour cells tested from patients with relapsed and refractory MM (84%), regardless of mutational status of RAS and BRAF genes. Importantly, BMSC-induced viability of MM patient cells was similarly blocked within the same dose range.
Supplier:
Enzo Life Sciences
Description:
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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