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Pyrazine-2,6-diamine+hydrochloride
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Pyrazine-2,6-diamine+hydrochloride
Catalog Number:
(89314-956)
Supplier:
Genetex
Description:
Conjugation: FITC Species Reactivity: Rabbit Tested Applications: FACS, IM Pkg Size: 500 ug
Catalog Number:
(102995-782)
Supplier:
Cell Sciences
Description:
Flow Cytometry: Use 10 µl to label 10E6 cells or 100 µl of whole blood.
Catalog Number:
(10069-592)
Supplier:
Prosci
Description:
Polyclonal, Host: Rabbit, Species Reactivity: Bacteria, Tested Applications: Western blotting
Supplier:
Adipogen
Description:
AV-412 is a potent dual inhibitor of EGFR and ErbB2 tyrosine kinases, including the mutant EGFR(L858R,T790M), which is clinically resistant to the EGFR-specific kinase inhibitors erlotinib and gefitinib. In enzyme assays assay the compound inhibited the EGFR variants and ErbB2 in the nanomolar range with over 100-fold selectivity compared with other kinases, apart from ABL and FLT1, which were both moderately sensitive to the compound. In cells, AV-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively. It also inhibited epidermal growth factor (EGF)-dependent cell proliferation with an IC(50) of 100nM. Moreover, AV-412 abrogated EGFR signaling in the gefitinib-resistant H1975 cell line, which harbors a double mutation of L858R and T790M in EGFR. In animal studies using cancer xenograft models, AV-412 (30mg/kg) demonstrated complete inhibition of tumor growth of the A431 and BT-474 cell lines, which overexpress EGFR and ErbB2, respectively.
Catalog Number:
(10392-034)
Supplier:
Bioss
Description:
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Catalog Number:
(10390-112)
Supplier:
Bioss
Description:
This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).
Catalog Number:
(89285-028)
Supplier:
Genetex
Description:
Mouse Monoclonal antibody to Brdu Clone: Bu20a Conjugation: FITC Species Reactivity: Chemical Pkg Size: 50 ug
Catalog Number:
(89285-196)
Supplier:
Genetex
Description:
Mouse Monoclonal antibody to Adenovirus Clone: 143 Conjugation: FITC Species Reactivity: Virus Pkg Size: 50 ug
Catalog Number:
(89307-520)
Supplier:
Genetex
Description:
Conjugation: FITC Purity: Affinity purified with antigen Species Reactivity: Rabbit Pkg Size: 500 ug
Catalog Number:
(10626-676)
Supplier:
Abnova
Description:
Rabbit polyclonal antibody raised against Borrelia burgdorferi.
Catalog Number:
(10395-230)
Supplier:
Bioss
Description:
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Catalog Number:
(10387-890)
Supplier:
Bioss
Description:
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
Catalog Number:
(10455-080)
Supplier:
Bioss
Description:
MAGEB4
Catalog Number:
(89277-590)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [LT7] to CD7
Catalog Number:
(89307-130)
Supplier:
Genetex
Description:
Clone: MARG2b-3 Conjugation: FITC Species Reactivity: Rat Tested Applications: FACS Pkg Size: 125 ug
Catalog Number:
(89336-148)
Supplier:
Genetex
Description:
FITC-conjugated Goat anti-Dog IgG Polyclonal antibody
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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