2-[(Acetylthio)methyl]-3-phenylpropionic+acid
Catalog Number:
(10261-422)
Supplier:
Bioss
Description:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
Catalog Number:
(10236-566)
Supplier:
Bioss
Description:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
Supplier:
TCI America
Description:
(stabilized with MEHQ)
CAS Number: 2455-24-5 MDL Number: MFCD00014515 Molecular Formula: C9H14O3 Molecular Weight: 170.21 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 85 Flash Point (°C): 96 Specific Gravity (20/20): 1.04
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 amino acid residues 1 to 21 tri-methylated at Lys-4 with a C-terminal GG linker followed by a biotinylated lysine. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ART-K(Me3)-QTARKSTGGKAPRKQLA-GGK(Biotin) MW:2765.2 Da % peak area by HPLC:95 Storage condition:-20° C
Supplier:
TCI America
Description:
CAS Number: 2917-65-9
MDL Number: MFCD00009650 Molecular Formula: C6H14O2Si Molecular Weight: 146.26 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 137 Flash Point (°C): 20 Specific Gravity (20/20): 0.88
Supplier:
MilliporeSigma
Description:
Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs
Catalog Number:
(76002-994)
Supplier:
Enzo Life Sciences
Description:
Cell permeable MIF antagonist with anti-inflammatory properties.
Catalog Number:
(AAJ63784-EXG)
Supplier:
Thermo Scientific Chemicals
Description:
This leptomycin B is a potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus.
Catalog Number:
(76012-120)
Supplier:
Prosci
Description:
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
Supplier:
AMBEED, INC
Description:
Boc-DL-β-Aib-OH 98%
Catalog Number:
(103008-370)
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 amino acid residues 1-21. It is monomethylated at arginine 17 with a C-terminal GG linker followed by a biotinylated lysine. The methylation of histone H3 at arginine 17 is linked with gene activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTARKSTGGKAP-R(Me1)-KQLA-GGK(Biotin)-NH2 MW:2736.2 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(89139-378)
Supplier:
Biotium
Description:
Rhodamine 123 is a popular green fluorescent mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. It is widely used in flow cytometry studies involving mitochondrial membrane potential.
Supplier:
Thermo Scientific Chemicals
Description:
Protein staining following gel electrophoresis
Supplier:
TCI America
Description:
CAS Number: 6757-06-8
MDL Number: MFCD00064355 Molecular Formula: C9H14N3O8P Molecular Weight: 367.16 Purity/Analysis Method: >99.0% (HPLC) Form: Crystal Specific rotation [a]20/D: 8 deg (C=2, H2O) Storage Temperature: 0-10°C
Supplier:
Adipogen
Description:
Activated ester of ruthenium complex for acylation of amino acid side chain amines. This label is perfectly suitable for 1D- or 2D-protein gel staining. A simple pre-electrophoresis procedure provides a sensitivity better than SYPRO Ruby and a similar dynamic range. In contrast to SYPRO Ruby, this staining exhibits a logarithmic dependency on the amount of protein.
Catalog Number:
(10289-296)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
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