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2-[Methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]isonicotinic+acid
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2-[Methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]isonicotinic+acid
Supplier:
AMBEED, INC
Description:
for Research Use Only
Supplier:
AMBEED, INC
Description:
Sodium 3-((-ethyl(-4-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-sulfonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)ammonio)methyl)benzenesulfonate, Purity: 97%, CAS Number: 5141-20-8, Red to Dark red to Dark purple powder to crystal, Storage: Inert atmosphere, Room Temperature, Size: 5G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041899-1G , MDL Number: MFCD02682284
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Supplier:
AMBEED, INC
Description:
4-Methyl-2-oxo-2H-chromene-3-carbonitrile, Purity: 97%, CAS Number: 24526-69-0, Appearance: White to blue to light green solid, Storage: Sealed in dry, 2-8 C, Size: 1g
Supplier:
AMBEED, INC
Description:
6-Bromo-2-methyl-2H-indazole 97%
Supplier:
AMBEED, INC
Description:
tert-Butyl isonicotinate 97%
Supplier:
MORAVEK BIOCHEMICALS MS
Description:
Tenofovir disoproxil fumarate
Supplier:
AOB CHEM USA
Description:
5,7-Dibromo-2-methyl-2H-indazole ≥97%
Supplier:
AOB CHEM USA
Description:
6-Bromo-2-methyl-2H-indazole ≥97%
Supplier:
AMBEED, INC
Description:
5-Methyl-1,3-dihydro-2H-benzimidazol-2-one 97%
Catalog Number:
(10075-532)
Supplier:
Prosci
Description:
Polyclonal, Host: Rabbit; Species Reactivity: Human, Mouse, Rat; Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser80 of MECP2 (Methyl-CpGBinding Protein 2) protein; Tested Applications: WB, IHC
Catalog Number:
(101851-988)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041490-5G , MDL Number: MFCD02094097
Supplier:
TCI America
Description:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-phenylalanine, Purity: >98.0%(HPLC)(T), CAS number: 77128-73-5, Molecular Formula: C25H23NO4, MW: 401.46, Synonym: Fmoc-N-Me-Phe-OH, N-Fmoc-N-methyl-L-phenylalanine, Size: 1G
Supplier:
Matrix Scientific
Description:
MF=C10H14CLN MW=183.68 CAS=861368-85-6 MDL=MFCD09026775 1G
Supplier:
Bachem Americas
Description:
Sequence: H-α-Me-D-Leu-OH
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