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BIOLEGEND
Supplier:
Adipogen
Description:
Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 (IL-1R1) and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed by phosphorylation of ERK1 (MAPK3) / ERK2 (MAPK1), p38 (MAPK14) and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases and sepsis. IL-33 facilitates Treg expansion in vitro and in vivo. Recently, IL-33 has been involved in adipocyte differentiation. The biological activity of IL-33 at its receptor ST2 is rapidly terminated in the extracellular environment by its oxidation (formation of two disulfide bridges), resulting in an extensive conformational change that disrupts the ST2 binding site. Mutations at amino acids C208S/C232S protect IL-33 from oxidation and increase its activity.
Catalog Number:
(76484-286)
Supplier:
AAT BIOQUEST INC
Description:
Hydrogen peroxide (H2O2) is a reactive oxygen metabolic by-product that serves as a key regulator for a number of oxidative stress-related states.
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00011440
Fieser: 1,871 7,291 10,319 15,267 18,293 20,309
Supplier:
BeanTown Chemical
Description:
CAS: 7440-69-9; EC No: 231-177-4; MDL No: MFCD00134033; RTECS: EB2600000
Solid; Molecular Formula: Bi; MW: 208.98
Melting Point: 271°; Boiling Point: 1560°
Density (g/mL): 9.8
Catalog Number:
(76700-450)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human Endothelial Nitric Oxide Synthase(eNOS) ELISA Kit
Catalog Number:
(76716-270)
Supplier:
AFG BIOSCIENCE LLC
Description:
Monkey Inducible Nitric Oxide Synthase,iNOS ELISA Kit
Catalog Number:
(76709-542)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human Advanced Oxidation Protein Products(AOPP) ELISA Kit
Catalog Number:
(77983-378)
Supplier:
LGC STANDARDS
Description:
Diphenyl(2,4,6-trimethylbenzoyl)phosphine Oxide, TRC, LGC Standards
Catalog Number:
(77537-708)
Supplier:
Bioss
Description:
Human Arsenic, 3-Oxidation State Methyltransferase (AS3MT) ELISA Kit
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00011220
Freely soluble in water and alcohol.
Supplier:
Thermo Scientific Chemicals
Description:
IDT-2BR, 5,5'-[[4,4,9,9-Tetrakis(4-hexylphenyl)-4,9-dihydro-s-indaceno[1,2-b:5,6-b']dithiophene-2,7-diyl]bis(2,1,3-benzothiadiazole-7,4-diylmethylidyne)]bis[3-ethyl-2-thioxo-4-thiazolidinone], Formula: C88H88N6O2S8, Formula Weight: 1518.20, Storage & Sensitivity: Ambient temperatures, Size: 250mg
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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