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6-Bromo-4-chloropyrido[2,3-d]pyrimidine
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6-Bromo-4-chloropyrido[2,3-d]pyrimidine
Catalog Number:
(75843-594)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The B122 monoclonal antibody specifically reacts with the precursor and mature secreted forms of mouse IL-1β and is cross-reactive with rat IL-1β. IL-1α and IL-1β are recognized by the same cell surface receptor but are generated from distinct genes. The B122 antibody is reported to neutralize the bioactivity of natural or recombinant IL-1β.
Catalog Number:
(75842-524)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex. The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The epitope that binds the MTS510 antibody is lost after LPS stimulation and the antibody can be used to co-immunoprecipitates MD-2 and TLR4.
Catalog Number:
(75843-526)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.
Catalog Number:
(75844-314)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Catalog Number:
(75842-344)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Catalog Number:
(75844-124)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HI100 monoclonal antibody specifically reacts with human CD45RA, the 220 kDa isoform of the human leukocyte common antigen (LCA) found on 40-50% of the peripheral CD4+ T lymphocytes, half of the peripheral CD8+ T lymphocytes and some of the monocytes and B lymphocytes. The CD45RA antigen is expressed by naïve and activated T lymphocytes. The HI100 monoclonal antibody is used as a phenotypic marker to discriminate T lymphocytes subsets.
Catalog Number:
(75841-600)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Catalog Number:
(75841-588)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.
Catalog Number:
(75842-748)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
Catalog Number:
(75842-746)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
Catalog Number:
(75842-814)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin α chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Catalog Number:
(75842-822)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin α chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
Catalog Number:
(75842-332)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Catalog Number:
(10351-442)
Supplier:
Bioss
Description:
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Catalog Number:
(10351-444)
Supplier:
Bioss
Description:
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Catalog Number:
(75842-338)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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