Catalog Number:
(10107-958)
Supplier:
Prosci
Description:
PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number:
(10783-222)
Supplier:
CHI Scientific
Description:
Kit, Primacell* 10 Mouse Brain FibrOut*10: Fibroblast Inhibitory System (for 500 ml medium), A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes, Stability: package should be stored at 4-8 degree C
Supplier:
BeanTown Chemical
Description:
CAS: 125572-95-4; EC No: 236-308-9; MDL No: MFCD00149243
Crystalline/Powder; Molecular Formula: C14H22N2O8·H2O ; MW: 364.35
Melting Point: 213-216°
Catalog Number:
(10426-392)
Supplier:
Bioss
Description:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Catalog Number:
(102121-836)
Supplier:
Novus Biologicals
Description:
The COX4 Antibody [DyLight 550] from Novus Biologicals is a rabbit polyclonal antibody to COX4. This antibody reacts with human, mouse, rat, porcine, bovine, drosophila, insect, primate. The COX4 Antibody [DyLight 550] has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(100503-674)
Supplier:
Electron Microscopy Sciences
Description:
Azur B/Methylene Blue/Eosin 1:1:1.
![]()
Catalog Number:
(10786-782)
Supplier:
CHI Scientific
Description:
Kit PrimaCell* 1 Human Intestine FibrOut* 1, Fibroblast Inhibitory System (for 500 ml medium), mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes, stable at 4-8 degreeC, effective up to 4
Catalog Number:
(EM1.15938.0100)
Supplier:
MilliporeSigma
Description:
Hematoxylin monohydrate (C.I.75290) for microscopy Certistain®
Hämatoxylin-Monohydrat (C.I. 75290) Certistain® is a dye for the specific staining of DNA in the nuclei. It is used in cytology and histology. Nuclei are stained blue, dark violet to black. Hematoxylins are mixed with trivalent positively charged metal salts and build up the so-called hematoxylin lakes, used for the selective staining of nuclei (DNA). Certistain® is the quality group for seleceted high quality dyes that fulfill all quality requirements for IVD and CE registration.
Catalog Number:
(10108-072)
Supplier:
Prosci
Description:
PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1 intronless gene which has similar functions. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. It also has two processed pseudogenes PCBP2P1 and PCBP2P2. There are presently two alternatively spliced transcript variants described for this gene.
Catalog Number:
(AAA19808-AE)
Catalog Number:
(101411-006)
Supplier:
Electron Microscopy Sciences
Description:
0.5% Aqueous
![]()
Catalog Number:
(10282-100)
Supplier:
Bioss
Description:
The inherited blindness associated protein, aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), interacts with the cell cycle regulator protein NUB1. AIPL1 is crucial for protein folding and stabilization, as well as for protein trafficking. It localizes to the nucleus or cytoplasm and is highly expressed in the pineal gland and the retina. In the retina, AIPL1 is expressed in both developing cone and rod photoreceptors, but it is restricted to rod photoreceptors in the adult human retina. Defects in the gene encoding for AIPL1 can cause Leber congenital amaurosis type IV, an early-onset, inherited autosomal recessive disorder that results in childhood blindness.
Supplier:
BeanTown Chemical
Description:
CAS: 941-69-5; EC No: 213-382-0; MDL No: MFCD00005502; RTECS: ON5950000
UN No: UN2811; Haz Class: 6.1; Packing Group: III
Flakes; Molecular Formula: C10H7NO2; MW: 173.17
Melting Point: 85-87°; Boiling Point: 162-163°/12 mmHg; Flash point: 152°C (306°F)
Density (g/mL): 1.18
Moisture Sensitive
Supplier:
AGILENT TECHNOLOGIES, INC (CSD)
Description:
Guarantees analysis of FAME cis/trans isomers in the C6 to C26 range.
Supplier:
Spectrum Chemicals
Description:
Rose Bengal can be used in synthetic chemistry to generate singlet oxygen from triplet oxygen.
![]()
Supplier:
ALADDIN SCIENTIFIC
Description:
ATC 0175 hydrochloride ≥98% (by HPLC)
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||