(S)-tert-Butyl+piperidine-2-carboxylate+hydrochloride
Supplier:
AOB CHEM USA
Description:
Benzyl 2,4-difluorophenyl ether ≥97%
Supplier:
TCI America
Description:
CAS Number: 117068-71-0
Molecular Formula: C12H10BrNO Molecular Weight: 264.12 Purity/Analysis Method: >97.0% (GC) Form: Crystal Freezing point (°C): 36 Storage Temperature: 0-10°C
Catalog Number:
(10291-718)
Supplier:
Bioss
Description:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
Catalog Number:
(10666-102)
Supplier:
Bioss
Description:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
Catalog Number:
(76011-616)
Supplier:
Prosci
Description:
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
Supplier:
Matrix Scientific
Description:
MF=C19H28N2O4 MW=348.45 CAS=878630-96-7 MDL=MFCD18207774 250MG
Supplier:
Thermo Scientific Chemicals
Description:
Grade: 98. Melting Point C173-175*. Boiling Point C: NA. C12H11NO2. 2683-66-1. IRRITANT
Catalog Number:
(10291-716)
Supplier:
Bioss
Description:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
Catalog Number:
(10291-722)
Supplier:
Bioss
Description:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
Supplier:
MilliporeSigma
Description:
Highly sensitive substrate for trypsin-like enzymes and granule-associated serine esterase.
Catalog Number:
(100271-384)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 3397-32-8 5gm Z-Phe-OSu 396.4 Room temperature.
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Catalog Number:
(103270-192)
Supplier:
Novus Biologicals
Description:
The C10orf35 Antibody from Novus Biologicals is a rabbit polyclonal antibody to C10orf35. This antibody reacts with human. The C10orf35 Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
Supplier:
AMBEED, INC
Description:
Pentaethylene glycol monobenzyl ether ≥95%, Ambeed.Inc
Catalog Number:
(103277-292)
Supplier:
Novus Biologicals
Description:
The Galectin-3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Galectin-3. This antibody reacts with human. The Galectin-3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number:
(103359-574)
Supplier:
Novus Biologicals
Description:
The TRAIL / TNFSF10 Antibody (55B709.3) [DyLight 650] from Novus Biologicals is a mouse monoclonal antibody to TRAIL / TNFSF10. This antibody reacts with human. The TRAIL / TNFSF10 Antibody (55B709.3) [DyLight 650] has been validated for the following applications: Western Blot, Immunohistochemistry-Paraffin.
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