Lithium+acetoacetate
Supplier:
TCI America
Description:
4,4,5,5-Tetramethyl-2-(2-methyl-1-propenyl)-1,3,2-dioxaborolane, Purity: >98.0%(GC), CAS Number: 126689-00-7, Molecular Formula: C10H19BO2, Molecular Weight: 182.07, Size: 5G
Catalog Number:
(10320-630)
Supplier:
Bioss
Description:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
Supplier:
TCI America
Description:
CAS Number: 39262-22-1
MDL Number: MFCD00064155 Molecular Formula: C10H15ClO3S Molecular Weight: 250.74 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 67 Specific rotation [a]20/D: -29.5 deg (C=1, CHCl3)
Catalog Number:
(10108-306)
Supplier:
Prosci
Description:
ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Supplier:
Ricca Chemical
Description:
1% (w/v) Aqueous. pH 4.6 (yellow) - 6.0 (pink). Container: Glass.
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Supplier:
BURKLE INC
Description:
Delivery tubes made of PP are resistant against weak acids, caustic solutions and detergents.
Delivery tubes made of PVDF are especially for acids and caustic solutions; not for strongly oxidizing acids and caustic solutions. Delivery tubes made of stainless steel 304 are for solvents and liquids of VbF Hazard Class AIII (not easily flammable). Battery pump for safe filling of car batteries with acid or distilled water.
Catalog Number:
(10740-564)
Supplier:
Abnova
Description:
Rabbit polyclonal antibody raised against synthetic peptide of TBC1D1.
Supplier:
TCI America
Description:
CAS Number: 39830-66-5
MDL Number: MFCD00191222 Molecular Formula: C10H9NO2 Molecular Weight: 175.19 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 71
Supplier:
TCI America
Description:
CAS Number: 50820-65-0
MDL Number: MFCD00211063 Molecular Formula: C10H9NO2 Molecular Weight: 175.19 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 77
Catalog Number:
(89517-036)
Supplier:
Abgent
Description:
Western Blot: 1:1000
Supplier:
Thermo Scientific Chemicals
Description:
4-Hydroxy-1-butanesulphonic acid sultone. Grade: 99, Melting Point C12-15*. Boiling Point C: 114-116*/1. 5mm. C4H8O3S. 1633-83-6. POSSIBLE MUTAGEN HARMFUL MOISTURE SENSITIVE
Supplier:
PeproTech, Inc.
Description:
CD40, a member of the TNF receptor superfamily, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to “immunodeficiency with hyper-IgM”, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. The soluble form of CD40L is an 18 kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Recombinant Murine sCD40 Ligand is a soluble 16.4 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.
Supplier:
Spectrum Chemicals
Description:
Dipotassium Dihydrogen Ethylenediaminetetraacetic Acid, Reagent
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Supplier:
Strem Chemicals Inc
Description:
CAS #: 25102-12-9. Size: 50g.
Supplier:
Adipogen
Description:
A sensitive reagent for measuring the free sulfhydryl content in proteins, peptides, and tissues. Used to characterize reactive thiol groups and photometric determination of thiols and for measuring low-molecular mass thiols such as glutathione in both pure solutions and biological samples, such as blood. It can also measure the number of thiol groups on proteins. Through reaction with aliphatic thiol groups a mixed disulfide of protein thiol and one mole of 2-nitro-5-thiobenzoate per mole of protein sulfhydryl group is being formed. DTNB has little absorbance. Reaction with -SH groups on proteins (from any solvent accessible Cys) under mild alkaline conditions (pH 7-8) produces the 2-nitro-5-thiobenzoate anion, which gives an intense yellow color with an absorption maximum at 409.5nm (Extinction coefficient: 14150 M-1*cm-1). Sensitive to various buffer ions, therefore, the extinction coefficient used to calculate the number of sulfhydryl groups must be matched to the reaction conditions. In case the thiol groups are in disulfide bonds, they must be reduced under anaerobic conditions prior to reaction with DTNB.
Catalog Number:
(89139-158)
Supplier:
Biotium
Description:
BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium. Key advantages of these calcium chelators include relative insensitivity toward intracellular pH change and fast release of calcium.
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