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Supplier:  Rockland Immunochemical
Description:   The whole sera are prepared from normal sera by a multi-step process that includes delipidation and selective precipitation
Small Business Enterprise Minority or Woman-Owned Business Enterprise

Supplier:  Rockland Immunochemical
Description:   This product is a convenient, ready-to-use solution of salmon sperm DNA especially prepared for use in the preparation of pre-hybridization and hybridization solutions and as a DNA carrier in yeast transformation protocols and other related methods
MSDS SDS
Small Business Enterprise Minority or Woman-Owned Business Enterprise
Catalog Number: (10664-636)

Supplier:  Bioss
Description:   Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming Ã¥ subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming Ã¥ subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.
Catalog Number: (89141-436)

Supplier:  Enzo Life Sciences
Description:   Adrenergic receptors mediate the hormone and neurotransmitter functions of adrenaline and noradrenaline. Adrenoreceptors function in peripheral tissues and the central nervous system to regulate numerous vascular, metabolic, and neurological functions, and are the target for many therapeutically relevant drugs including those for the treatment of hypertension, asthma, benign prostatic hypertrophy, and depression. Adrenoreceptors are classified by three types (α1, α2, and β) and multiple subclasses based on pharmacological and molecular characteristics. The α1 family consists of three receptor subtypes (α1a, 1b, 1d) which primarily signal via Gq/11 alpha subunits to stimulate Phospholipase C and increase intracellular calcium. In contrast, the three α2 family receptor subtypes (α2a, 2b, 2c) signal via Gi/o alpha subunits to inhibit adenylyl cyclase activity, increase potassium transport, inhibit calcium conductance, and stimulate phospholipase A2. α1b adrenergic receptor mRNA expression in human tissues is highest in the spleen, kidney, and fetal brain. The α2a receptor is most highly expressed in human brain, spleen, and kidney, and is a species orthologue of the α2d receptor expressed similarly in rat, mouse, and cow.
Supplier:  MP Biomedicals
Description:   Chloroplatinic acid is used in potassium determination, purification of platinum and in catalysis.
MSDS SDS
Supplier:  Bioss
Description:   Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Supplier:  Bioss
Description:   Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Catalog Number: (RL213-4107)

Supplier:  Rockland Immunochemical
Description:   Secondary Rabbit Anti-IgM mu chain Reacts with Sheep (Ovine)
Catalog Number: (10792-730)

Supplier:  Genetex
Description:   Rabbit Polyclonal antibody to Kv4.2
Catalog Number: (RL609-6102)

Supplier:  Rockland Immunochemical
Description:   Secondary Sheep Anti-IgG (H&L) Reacts with Human
Supplier:  Bioss
Description:   Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.

Supplier:  Bioss
Description:   Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.

Supplier:  Electron Microscopy Sciences
Description:   NaHCO3 F.W. 84.01 CAS 144-55-8 Assay 97.7-100.3%
Minority or Woman-Owned Business Enterprise
Catalog Number: (RL604-1102)

Supplier:  Rockland Immunochemical
Description:   Secondary Goat Anti-IgG (H&L) Reacts with Dog (Canine)

Supplier:  Rockland Immunochemical
Description:   Secondary Goat Anti-IgG (H&L) Reacts with Human
Catalog Number: (75935-082)

Supplier:  Rockland Immunochemical
Description:   Lyophilized Gamma Globulin Fraction
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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