Catalog Number:
(89415-336)
Supplier:
Prosci
Description:
APP Antibody: Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the brains of all suffers of Alzheimer's disease.
Catalog Number:
(101928-366)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064783-500MG , MDL Number: MFCD18064664
Catalog Number:
(77438-992)
Supplier:
Bioss
Description:
Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.
Catalog Number:
(77439-672)
Supplier:
Bioss
Description:
Anti-Inhibin beta A Rabbit Polyclonal Antibody
Catalog Number:
(77042-354)
Supplier:
ANTIBODIES.COM LLC
Description:
Rabbit polyclonal antibody to CaMK2 beta + gamma + delta for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Supplier:
ANTIBODIES.COM LLC
Description:
Mouse monoclonal [6A10] antibody to beta Synuclein for WB, ICC/IF and IHC with samples derived from Human, Rat, Mouse, Bovine and Porcine.
Catalog Number:
(10235-656)
Supplier:
Bioss
Description:
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Lactitol Impurity 1 (3-O-beta-D-Galactopyranosyl-D-Glucitol)
Catalog Number:
(102165-696)
Supplier:
Novus Biologicals
Description:
Rabbit Polyclonal IKK beta Antibody. Tested Applications: Western Blot. Tested Reactivity: Human.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Methyl-1-hydroxy-2-naphthoate
Catalog Number:
(102513-044)
Supplier:
Adipogen
Description:
Human CD49f molecules are integrin alpha 6 chains that are expressed as heterodimers with CD29 (beta 1 integrin) or CD104 (beta 4 integrin) and function as adhesion receptors. CD49f is expressed on platelets, monocytes, T lymphocytes and thymoctyes.
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Catalog Number:
(77074-114)
Supplier:
ANTIBODIES.COM LLC
Description:
Goat polyclonal antibody to PP2A alpha + beta for ELISA, WB and IHC with samples derived from Human, Mouse, Rat and Porcine.
Supplier:
AMBEED, INC
Description:
4-Benzyl-L-aspartate 97%
Catalog Number:
(ABCA_AB24693-100UG)
Supplier:
ABCAM INC.
Description:
Anti-Integrin beta 1 Mouse Monoclonal Antibody [clone: P5D2]
Catalog Number:
(ABCA_AB288429-200U)
Supplier:
ABCAM INC.
Description:
Anti-Integrin beta 7 Rat Monoclonal Antibody [clone: FIB504]
Supplier:
ABCAM INC.
Description:
Anti-Integrin beta 1 Rabbit Monoclonal Antibody [clone: EPR1040Y]
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