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2-Hydroxy-4,6-dimethylnicotinamide
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2-Hydroxy-4,6-dimethylnicotinamide
Catalog Number:
(ALA413612-25MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
APD668 832714-46-2 25MG
Catalog Number:
(77902-931)
Supplier:
AMBEED, INC
Description:
A462182 89336-46-9 5G
Catalog Number:
(102876-212)
Supplier:
R&D Systems
Description:
QNZ 46 (10 MG)
Catalog Number:
(77910-535)
Supplier:
AMBEED, INC
Description:
A400189 1243143-46-5 1G
Catalog Number:
(77939-861)
Supplier:
AMBEED, INC
Description:
A384254 15561-46-3 1G
Catalog Number:
(10304-938)
Supplier:
Bioss
Description:
ADAM13 was first described as a protein expressed in somatic mesoderm and neural crest cells, in developing Xenopus embryos. ADAM13 was also found in liver, heart, and intestines from adult Xenopus. ADAM13 may regulate cellular signaling via Src and Src tyrosine kinase. ADAM13 may also act as a cell attachment molecule, by binding integrins through the cysteine rich domain amoung many other roles. A member of the metalloproteinase family containing disintegrin like domains (ADAMs) the functions of ADAM13 are still poorly understood. ADAM13 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, as well as disintegrin, cysteine rich, EFG like, transmembrane and Cytoplasmic domains. ADAM13 has been shown to be proteolytically active, cleaving fibronectin after binding it to the EGF like domain. ADAM13 is also shed from cells in culture, cleaved aminoterminal from the transmembrane domain, and is released into the culture media. Shed ADAM13 is a 52 kD protein, and can form complexes with a2 macroglobulin, suggesting it is a competent protease. Xenopus ADAM13 has greatest homology with human ADAM 33 (51% identical), and is 46% identical with human or mouse ADAM12 or ADAM19. It is still unclear if any of these ADAMs are species orthologs of Xenopus ADAM13, but there are significant differences between the related sequences, suggesting that ADAM13 may be a unique protein. The full length Xenopus ADAM13 sequence codes for a 914 amino acid protein. Predicted mass is 99.749 kD, but glycosylation and cyteine rich regions give Xenopus ADAM13 an apparent MW of 120 kD unprocessed, and 97 kD processed forms, on reduced SDS PAGE gels. ADAM13 contains a putative furin cleavage site, suggesting that a prohormone convertase cleaves the propeptide domain away from the catalytic domain
Catalog Number:
(97051-314)
Supplier:
MicroSolv Technology Corp
Description:
HPS C18 4.6 X250MM
Catalog Number:
(76348-034)
Supplier:
RPI
Description:
RIFAMPICIN 13292-46-1 5G
Catalog Number:
(77942-916)
Supplier:
AMBEED, INC
Description:
A1505060 18197-46-1 1G
Catalog Number:
(77945-240)
Supplier:
AMBEED, INC
Description:
A407556 220396-46-3 100MG
Catalog Number:
(77943-653)
Supplier:
AMBEED, INC
Description:
A117258 97944-46-2 5G
Catalog Number:
(77943-083)
Supplier:
AMBEED, INC
Description:
A210547 245349-46-6 25G
Catalog Number:
(77922-560)
Supplier:
AMBEED, INC
Description:
A816664 1213519-46-0 250MG
Catalog Number:
(77940-403)
Supplier:
AMBEED, INC
Description:
A215132 125-46-2 100G
Catalog Number:
(77909-888)
Supplier:
AMBEED, INC
Description:
A941809 183990-46-7 5G
Catalog Number:
(ALA413612-10MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
APD668 832714-46-2 10MG
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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