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3-[(1,6-Dibromo-2-naphthyl)oxy]pyrrolidine+hydrochloride
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3-[(1,6-Dibromo-2-naphthyl)oxy]pyrrolidine+hydrochloride
Catalog Number:
(10298-800)
Supplier:
Bioss
Description:
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].
Catalog Number:
(10281-614)
Supplier:
Bioss
Description:
BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
Catalog Number:
(10405-504)
Supplier:
Bioss
Description:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice.
Catalog Number:
(10407-378)
Supplier:
Bioss
Description:
Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Catalog Number:
(76957-052)
Supplier:
ANTIBODIES.COM LLC
Description:
Mouse monoclonal [TUBB3/3732] antibody to beta III Tubulin for IHC-P with samples derived from Human.
Catalog Number:
(76954-616)
Supplier:
ANTIBODIES.COM LLC
Description:
Mouse monoclonal [12F7] antibody to beta Catenin for Flow Cytometry, IF and WB with samples derived from Human, Mouse and Rat.
Supplier:
AMBEED, INC
Description:
((3aR,4R,6R,6aR)-6-Methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol, Purity: 95%, CAS Number: 4099-85-8, Appearance: Colorless to Yellow Liquid, Storage: Inert atmosphere, 2-8C, Size: 250MG
Catalog Number:
(10800-086)
Supplier:
Rockland Immunochemical
Description:
Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by one of two beta-secretases (BACE and BACE2), producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the Alzheimer's disease patient's brains. Recently, Death Receptor 6 (DR6) was found to interact with an amino-terminal fragment of the Beta-amyloid protein (N-APP) in neurons, activating a caspase 6-dependent apoptotic event leading to axonal degeneration and pruning during development, suggesting that these two proteins are involved in neural development and may possibly play a role in Alzheimer's disease.
Catalog Number:
(103663-406)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human FGFR2(beta(IIIc)) (NP_001138387.1) (Met1-Glu288) was expressed with a polyhistidine tag at the C-terminus.
Catalog Number:
(89319-490)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to PSG6 (pregnancy specific beta-1-glycoprotein 6)
Catalog Number:
(76956-116)
Supplier:
ANTIBODIES.COM LLC
Description:
Mouse monoclonal [S100B/4149] antibody to S100 beta for IHC-P with samples derived from Human.
Supplier:
ALADDIN SCIENTIFIC
Description:
5-(4-Hydroxyphenethyl)benzene-1,3-diol ≥98%
Catalog Number:
(102511-734)
Supplier:
Adipogen
Description:
Human T cell receptor (TCR) is a T cell surface expressed heterodimer of alpha/beta or gamma/delta chains. TCR’s recognize antigen peptides bound to MHC molecules forming the basis of antigen specific response by T cells.
Catalog Number:
(10232-596)
Supplier:
Bioss
Description:
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Catalog Number:
(77519-710)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human MGAT5 (Mannosyl Alpha-1,6-Glycoprotein Beta-1,6-N-Acetylglucosaminyltransferase) ELISA Kit
Catalog Number:
(76701-844)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat Interleukin-12 Receptor Subunit beta-1 (IL12RB1/IL12R/IL12RB) ELISA Kit
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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