2-Methoxyphenyl+isothiocyanate
Catalog Number:
(10230-312)
Supplier:
Bioss
Description:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Catalog Number:
(10230-480)
Supplier:
Bioss
Description:
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Catalog Number:
(10337-792)
Supplier:
Bioss
Description:
Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
Catalog Number:
(10230-648)
Supplier:
Bioss
Description:
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity).
Catalog Number:
(10406-732)
Supplier:
Bioss
Description:
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Catalog Number:
(10416-032)
Supplier:
Bioss
Description:
Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility (By similarity).
Catalog Number:
(10349-360)
Supplier:
Bioss
Description:
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
Catalog Number:
(10403-850)
Supplier:
Bioss
Description:
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Catalog Number:
(10404-544)
Supplier:
Bioss
Description:
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
Catalog Number:
(10470-898)
Supplier:
Bioss
Description:
MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2 is a homolog of MAD2L1.
Catalog Number:
(10432-404)
Supplier:
Bioss
Description:
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Catalog Number:
(10466-112)
Supplier:
Bioss
Description:
MFF belongs to the tango11 family and plays a role in mitochondrial and peroxisomal fission. It is highly expressed in heart, kidney, liver, brain, muscle and stomach. There are five named isoforms.
Catalog Number:
(10470-178)
Supplier:
Bioss
Description:
May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
Catalog Number:
(10429-718)
Supplier:
Bioss
Description:
Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Catalog Number:
(10399-742)
Supplier:
Bioss
Description:
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Catalog Number:
(10672-122)
Supplier:
Bioss
Description:
VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA binding domain.
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