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2-Methoxyphenyl+isothiocyanate
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2-Methoxyphenyl+isothiocyanate
Catalog Number:
(10283-736)
Supplier:
Bioss
Description:
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Catalog Number:
(10302-968)
Supplier:
Bioss
Description:
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Catalog Number:
(10238-844)
Supplier:
Bioss
Description:
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Catalog Number:
(10284-686)
Supplier:
Bioss
Description:
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Catalog Number:
(10362-718)
Supplier:
Bioss
Description:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Catalog Number:
(10277-930)
Supplier:
Bioss
Description:
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.
Catalog Number:
(103367-842)
Supplier:
Novus Biologicals
Description:
The ATM Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to ATM. This antibody reacts with human, mouse. The ATM Antibody [FITC] has been validated for the following applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(103393-006)
Supplier:
Novus Biologicals
Description:
The Goat anti-Mouse IgG (H+L) Secondary Antibody [FITC] (Pre-absorbed) from Novus Biologicals is a goat polyclonal antibody to IgG (H+L). This antibody reacts with mouse. The Goat anti-Mouse IgG (H+L) Secondary Antibody [FITC] (Pre-absorbed) has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(103392-654)
Supplier:
Novus Biologicals
Description:
The Goat anti-Human IgG (H+L) Secondary Antibody [FITC] (Pre-absorbed) from Novus Biologicals is a goat polyclonal antibody to IgG (H+L). This antibody reacts with human. The Goat anti-Human IgG (H+L) Secondary Antibody [FITC] (Pre-absorbed) has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(103393-134)
Supplier:
Novus Biologicals
Description:
The Goat F(ab')2 anti-Mouse IgG (H+L) Secondary Antibody [FITC] from Novus Biologicals is a goat polyclonal antibody to IgG (H+L). This antibody reacts with mouse. The Goat F(ab')2 anti-Mouse IgG (H+L) Secondary Antibody [FITC] has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(103393-144)
Supplier:
Novus Biologicals
Description:
The Goat anti-Rabbit IgG (H+L) Secondary Antibody [FITC] (Pre-absorbed) from Novus Biologicals is a goat polyclonal antibody to IgG (H+L). This antibody reacts with rabbit. The Goat anti-Rabbit IgG (H+L) Secondary Antibody [FITC] (Pre-absorbed) has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(103368-970)
Supplier:
Novus Biologicals
Description:
The SREBP1 Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to SREBP1. This antibody reacts with human, mouse, rat, porcine, bovine, plant. The SREBP1 Antibody [FITC] has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(10334-722)
Supplier:
Bioss
Description:
Amphiphysin is associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for auto against this protein. Alternate splicing of this gene results in two transcript variants (Amphiphysin 1 and Amphiphysin 2) encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.
Catalog Number:
(10231-958)
Supplier:
Bioss
Description:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Catalog Number:
(10339-892)
Supplier:
Bioss
Description:
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Catalog Number:
(10327-584)
Supplier:
Bioss
Description:
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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