2-Phenylethyl+formate
Catalog Number:
(10338-700)
Supplier:
Bioss
Description:
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Catalog Number:
(10328-292)
Supplier:
Bioss
Description:
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Catalog Number:
(10474-304)
Supplier:
Bioss
Description:
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Catalog Number:
(10290-162)
Supplier:
Bioss
Description:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
Catalog Number:
(10082-110)
Supplier:
Proteintech
Description:
Anti-CALPAIN 3(Polyclonal) Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-156 amino acid, Format:Antigen affinity purification, Application: ELISA, Recommended Storage: - 20 C or lower
Catalog Number:
(10081-214)
Supplier:
Proteintech
Description:
Anti-ICA1L(Polyclonal) Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-187 amino acid, Format:Antigen affinity purification, Application: ELISA, IF, Recommended Storage: - 20 C or lower
Supplier:
Corning
Description:
Axygen® automation tips are engineered to the exact specifications of the original equipment manufacturers’ tips, ensuring complete compatibility and a consistent fit.
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Supplier:
HICHROM LIMITED
Description:
LiChrospher® is a silica available in both endcapped and non-endcapped C8 and C18 phases.
Catalog Number:
(10352-400)
Supplier:
Bioss
Description:
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
Catalog Number:
(10352-408)
Supplier:
Bioss
Description:
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
Catalog Number:
(76108-122)
Supplier:
Bioss
Description:
Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
Supplier:
Tonbo Biosciences
Description:
Monoclonal Antibody Anti-Mouse LY-6G(1A8) Isotype: Rat IgG2a, kappa Format: PERCP-CY5.5 Alternative Name: Gr-1 Concentration: 0.2 mg/mL
Catalog Number:
(82022-448)
Supplier:
G-Biosciences
Description:
OneQuant ActiveHOOKâ„¢ BSA is a pre-activated form of immunological grade BSA (MW 67kD) that has been activated by sulfoSMCC and is ready for direct coupling with peptides through the cysteine residues. Immunological grade BSA is a high purity grade bovine serum albumin (BSA) prepared for immunotechnology research applications such as a carrier protein for antibody production. ActiveHOOKâ„¢ BSA is supplied lyophilized in OneQuantâ„¢ format; 2mg/vial.
Catalog Number:
(10397-052)
Supplier:
Bioss
Description:
The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Catalog Number:
(AA31499-30)
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00014165
Decomposes in water with formation of As(OH)3 and HCl. Increasing dilutions in water result in As2O3 precipitation
Catalog Number:
(10797-304)
Supplier:
Prosci
Description:
Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via ?-catenin mediated Pdgfr? and E-cadherin expression.
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