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2-Phenylethyl+formate
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2-Phenylethyl+formate
Catalog Number:
(10106-496)
Supplier:
Prosci
Description:
The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
Catalog Number:
(10289-214)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context. Inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts. In quiescent vessels, ANGPT1 oligomers recruit TEK to cell-cell contacts, forming complexes with TEK molecules from adjoining cells, and this leads to preferential activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascades. In migrating endothelial cells that lack cell-cell adhesions, ANGT1 recruits TEK to contacts with the extracellular matrix, leading to the formation of focal adhesion complexes, activation of PTK2/FAK and of the downstream kinases MAPK1/ERK2 and MAPK3/ERK1, and ultimately to the stimulation of sprouting angiogenesis. ANGPT1 signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. Signaling is modulated by ANGPT2 that has lower affinity for TEK, can promote TEK autophosphorylation in the absence of ANGPT1, but inhibits ANGPT1-mediated signaling by competing for the same binding site. Signaling is also modulated by formation of heterodimers with TIE1, and by proteolytic processing that gives rise to a soluble TEK extracellular domain. The soluble extracellular domain modulates signaling by functioning as decoy receptor for angiopoietins. TEK phosphorylates DOK2, GRB7, GRB14, PIK3R1; SHC1 and TIE1.
Catalog Number:
(10050-980)
Supplier:
Tonbo Biosciences
Description:
The LTF-2 immunoglobulin is useful as an isotype-matched control. The LTF-2 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2b antibodies.
Catalog Number:
(PI23290)
Supplier:
Invitrogen
Description:
The Thermo Scientific™ Pierce™ Quantitative Fluorescent Peptide Assay is a sensitive, mix-and-read fluorescent microplate assay for the quantitative measurement of peptides and peptide mixtures.Sensitive—accurately detect as little as 5.0 µg/mL of single peptides or peptide mixturesRobust— assay performance rigorously tested using both peptides and peptide digest mixturesRobust peptide digest standard—kit includes a validated peptide digest standard for improved reproducibility of quantitationCompatible—works with many reagents, including those used in mass spectrometry sample preparationConvenient—easy mix-and-read format and stable fluorescent signal that may be read in as little as 5 minutes up to several hoursThe Pierce Quantitative Fluorescent Peptide Assay reagents include peptide assay buffer, fluorescent peptide labeling reagent, and a peptide digest assay standard for the quantitative measurement of peptide concentrations
Supplier:
AZENTA US, INC
Description:
Azenta Life Sciences 2D coded tubes provide a lifelong and secure chain of custody for samples in biobanks, compound libraries and a broad range of biological and chemical stores, including cryogenic storage.
Supplier:
AZENTA US, INC
Description:
Azenta Life Sciences 2D coded tubes provide a lifelong and secure chain of custody for samples in biobanks, compound libraries and a broad range of biological and chemical stores, including cryogenic storage.
Catalog Number:
(76467-398)
Supplier:
Boster Biological Technology
Description:
The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Human Retinol-Binding Protein 4/RBP4 with <10 pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: cell culture supernatants, serum, plasma (heparin, EDTA) and urine. This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. Retinol-Binding Protein 4/RBP4 tissue specificity:
Catalog Number:
(10051-326)
Supplier:
Tonbo Biosciences
Description:
The LTF-2 immunoglobulin is useful as an isotype-matched control. The LTF-2 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2b antibodies.
Catalog Number:
(76467-404)
Supplier:
Boster Biological Technology
Description:
The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Human Plasminogen/PLG with <10 pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: serum, plasma and cell culture supernatants. This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. Plasminogen/PLG tissue specificity: Present in plasma and many other extracellular fluids. It is synthesized in the liver.
Catalog Number:
(103051-112)
Supplier:
Charles River Laboratories Cell Solutions
Description:
Plasma is collected from IRB-consented volunteer donors diagnosed with Prostate Cancer.
Supplier:
HORIBA INSTRUMENTS INCORPORATED
Description:
Uric Acid Reagent Set is used for the quantitative determination of Uric Acid in serum.
Catalog Number:
(76467-394)
Supplier:
Boster Biological Technology
Description:
The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Human Gitr/TNFRSF18 with <10 pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. Gitr/TNFRSF18 tissue specificity: Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Catalog Number:
(76467-344)
Supplier:
Boster Biological Technology
Description:
The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Mouse Osteoprotegerin/TNFRSF11B with <5 pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: cell culture supernatants, serum and plasma (EDTA). This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. Osteoprotegerin/TNFRSF11B tissue specificity: Highly expressed in liver, lung, stomach, intestines and calvaria. Highly expressed in decidua and placenta, and in embryo.
Catalog Number:
(10022-900)
Supplier:
HORIBA INSTRUMENTS INCORPORATED
Description:
Triglycerides - Liquid Reagent Set is used for the in vitro quantitative determination of Triglycerides in serum or plasma.
Catalog Number:
(10051-850)
Supplier:
Tonbo Biosciences
Description:
The HRPN immunoglobulin is useful as an isotype-matched control. The HRPN immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG1 antibodies.
Catalog Number:
(89356-126)
Supplier:
Genetex
Description:
Corticosterone is a steroid hormone secreted by the outer layer, or cortex, of the adrenal gland . Classed as a glucocorticoid, corticosterone helps regulate the conversion of amino acids into carbohydrates and glycogen by the liver, and helps stimulate glycogen formation in the tissues. Corticosterone is similar in structure, although somewhat less potent, than the other glucocorticoids cortisol and cortisone . It is produced in response to stimulation by the pituitary substance adrenocorticotropic hormone (ACTH). In some species, but not in humans, corticosterone is the predominant glucocorticoid secreted by the adrenal. It is a precursor in the synthesis of aldosterone , another adrenal cortical steroid. Corticosterone Levels1. Men 420 ± 220 pg/0.1 ml2. Women Follicular Phase 240 ± 150 pg/0.1 ml Luteal Phase 440 ± 230 pg/0.1 ml3. Laying Hens 220 ± 50 pg/0.1 ml
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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