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2-(Benzylamino)isonicotinic+acid
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2-(Benzylamino)isonicotinic+acid
Supplier:
Adipogen
Description:
Masitinib is a potent, orally available protein tyrosine kinase inhibitor targeting c-Kit, PDGFR and FGFR3. It demonstrates activity for Kit and PDGFRalpha/beta with IC(50) values of 200nM, 540nM and 800nM respectively. It shows weak inhibition of ABL and c-Fms.
Catalog Number:
(75933-872)
Supplier:
Rockland Immunochemical
Description:
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Catalog Number:
(89158-262)
Supplier:
Enzo Life Sciences
Description:
Cell permeable inhibitor of RhoA- and RhoC-mediated signaling. Inhibits LPA-induced DNA synthesis in PC-3 prostate cancer cell lines (<1µM) and inhibits the growth of RhoC-overexpressing melanoma cell lines (A375M2 and SK-Mel-147) at nanomolar concentrations.
Catalog Number:
(103009-844)
Supplier:
Anaspec Inc
Description:
This peptide is Histone 3 amino acid residues 21 to 44. It is mono-methylated at Lys27 and Lys36 with a C-terminal G linker followed by a biotinylated lysine. Histone methylation plays an important role in the regulation of chromatin structure and function. Related Peptides: [Lys(Ac)27, Lys(Me1)36]-Histone H3 (21-44)-GK(Biotin), H3K27(Ac)K36(Me1), biotin-labeled, Cat# 65444 [Lys(Ac)27, Lys(Me2)36]-Histone H3 (21-44)-GK(Biotin), H3K27(Ac)K36(Me2), biotin-labeled, Cat# 65445
Sequence:ATKAAR-K(Me1)-SAPATGGV-K(Me1)-KPHRYRPG-GK(Biotin) MW:2946.5 Da % peak area by HPLC:95 Storage condition:-20° C
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 021407-25G , MDL Number: MFCD00066332
Catalog Number:
(103008-616)
Supplier:
Anaspec Inc
Description:
This peptide is histone H3 amino acid residues 1 to 21. It is asymmetrically dimethylated at arginine 8 with both methyl groups added to one nitrogen of the guanidinium group, and contains a C-terminal biotinylated lysine.
Sequence:ARTKQTA-R(Me2a)-KSTGGKAPRKQLA-K(Biotin)-NH2 MW:2636.1 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(10236-562)
Supplier:
Bioss
Description:
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
Catalog Number:
(102535-796)
Supplier:
Matrix Scientific
Description:
MF=C7H8BRN MW=186.06 CAS=583-68-6 MDL=MFCD00007635 10G
Catalog Number:
(102536-238)
Supplier:
Matrix Scientific
Description:
MF=C7H8BRN MW=186.06 CAS=7745-91-7 MDL=MFCD00134176 100G
Supplier:
BeanTown Chemical
Description:
CAS: 55289-36-6; EC No: 259-568-5; MDL No: MFCD00051579
UN No: UN2810; Haz Class: 6.1; Packing Group: III
Solid; Molecular Formula: C7H8BrN; MW: 186.05
Boiling Point: 248°; Flash point: 110°C (230°F)
Density (g/mL): 1.51; Refractive Index: 1.619
Light Sensitive
Catalog Number:
(101919-462)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059925-1G , MDL Number: MFCD09878605
Supplier:
TCI America
Description:
CAS Number: 34369-07-8
MDL Number: MFCD00080339 Molecular Formula: C10H16N5O13P3 Molecular Weight: 551.14 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Specific rotation [a]20/D: -19 deg (C=3, H2O) Storage Temperature: 0-10°C
Catalog Number:
(10166-878)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to Histone H4 (tri methyl Lys20) (histone cluster 1, H4a)
Catalog Number:
(76483-566)
Supplier:
AAT BIOQUEST INC
Description:
Positively charged rhodamine dyes (such as rhodamine esters and rosamines) are selectively localized in mitochondria, thus they are widely used for labeling mitochondria of live cells.
Supplier:
BeanTown Chemical
Description:
CAS: 615-65-6; EC No: 210-440-7; MDL No: MFCD00007666; RTECS: XU5110000
UN No: UN3429; Haz Class: 6.1; Packing Group: III
Liquid; Molecular Formula: C7H8ClN; MW: 141.60
Melting Point: 7°; Flash point: 99°C (210°F)
Density (g/mL): 1.151 ; Refractive Index: 1.575
Catalog Number:
(76002-048)
Supplier:
Enzo Life Sciences
Description:
PI3 kinase inhibitor
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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