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3,4-Bis(1-methylethoxy)benzoic+acid
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3,4-Bis(1-methylethoxy)benzoic+acid
Supplier:
TCI America
Description:
CAS Number: 16225-26-6
MDL Number: MFCD00082727 Molecular Formula: C15H22O2 Molecular Weight: 234.34 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 173
Catalog Number:
(76121-200)
Supplier:
Bioss
Description:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65000. The human albumin gene is 16961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
Supplier:
AMBEED, INC
Description:
3,5-Di-tert-butyl-4-hydroxybenzoic acid 98%
Supplier:
TCI America
Description:
CAS Number: 1421-49-4
MDL Number: MFCD00008827 Molecular Formula: C15H22O3 Molecular Weight: 250.34 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 210
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Bis(2-oxo-3-oxazolidinyl)phosphinic chloride 97%
Catalog Number:
(76010-108)
Supplier:
Prosci
Description:
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Catalog Number:
(IC0210116625)
Supplier:
MP Biomedicals
Description:
β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of two oxidation-reduction coenzymes: nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). The nicotinamide portion of the coenzyme transfers hydrogens by alternating between oxidized quaternary nitrogen and a reduced tertiary nitrogen. NADP is an essential coenzyme for glucose-6-phosphate dehydrogenase which catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconic acid. This reaction initiates metabolism of glucose by a pathway other than the citric acid cycle. This route is known as the hexose phosphate shunt or phosphogluconate pathway. Other enzymes which utilize NADP as a coenzyme are: Alcohol dehydrogenase:NADP dependent; Aromatic ADH:NADP dependent; Ferredoxin-NADP reductase; L-Fucose dehydrogenase; Gabase; Galactose-1-phosphate uridyl transferase; Glucose dehydrogenase; L-Glutamic dehydrogenase; Glycerol dehydrogenase:NADP specific; Isocitric dehydrogenase; Malic enzymes; 5,10-Methylenetetrahydrofolate dehydrogenase; 6-Phosphogluconate dehydrogenase and Succinic semialdehyde dehydrogenase.
Supplier:
Adipogen
Description:
The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. Useful vital stain for the flow cytometric recognition of DNA damage and other viability measurements by monitoring the emission spectral shifts of the dyes. Because this fluorescent stain labels DNA, it can also be used to visualize nuclei and mitochondria. Hoechst 34580 can be excited by violet laser at 405 nm, and emit blue/cyan fluorescence light around an emission maximum at ~440 nm. It is cell-permeable and an excellent tool for flow cytometry studies.
Supplier:
Adipogen
Description:
Potent anticancer compound. Anti-angiogenic. VEGF, VE-cadherin phosphorylation, matrix metalloproteinase and urokinase-plasminogen activator (uPA) inhibitor. Anti-inflammatory. NF-kappaB inhibitor. Modulates chronic inflammatory diseases, such as type 2 diabetes, rheumatoid arthritis, inflammatory bowel disease. COX-2 and inducible nitric oxide synthase (iNOS; NOS II) inhibitor. Potent antioxidant. Protects cells from lipid peroxidation and DNA damage induced by reactive free radicals. Regulates cancer cell growth, proliferation, transformation, survival, angiogenesis, apoptosis, invasion and metastasis. Chemopreventive. Apoptosis inducer. Promotes cell cycle arrest. Modulates signal transduction pathways including JAK/STAT, MAPK, PI3K/AKT, Wnt and Notch. EGFR and HER-2 receptor signaling inhibitor. MAPKs and activator protein-1 inhibitor. mTOR suppressor. IGF-I signaling inhibitor. Proteasome inhibitor. Telomerase and DNA methyltransferase inhibitor. Selective and noncompetitive HAT inhibitor. Topoisomerase I and II inhibitor. Hedgehog signaling (Hh) modulator. PTCH and Gli1 inhibitor. Wnt signaling inhibitor. Neuroprotective. Activates HO-1 by the ARE/Nrf2 pathway, protecting neurons against oxidative damage. STAT-1 inhibitor. Shows preventive cardiovascular and metabolic (obesity, insulin resistance, hypertension and hypercholesterolemia) effects. Inhibits extracellular signal-related kinases (ERK), activates AMP-activated protein kinase (AMPK), modulates adipocyte marker proteins and down-regulates lipogenic enzymes as well as other potential targets. Fatty acid synthase (FAS) inhibitor. Autophagy stimulator.
Supplier:
TCI America
Description:
CAS Number: 6155-57-3
MDL Number: MFCD00151213 Molecular Formula: C7H5NO3S Molecular Weight: 205.16 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 228
Catalog Number:
(10049-832)
Supplier:
Enzo Life Sciences
Description:
Cyclooxygenases-1 and 2 (COX-1 and COX-2), also known as prostaglandin endoperoxide H synthases-1 and 2, are integral membrane proteins which catalyze the first step of prostaglandin, thromboxane and prostacyclin production from arachidonic acid. Both COX-1 and COX-2 catalyze a cyclooxygenase (bis-oxygenase) reaction in which arachidonate plus two molecules of O2 are converted to PGG2 (prostaglandin G2), and a peroxidase reaction in which PGG2 undergoes a two-electron reduction to PGH2. COX-1 and COX-2 proteins are encoded by separate genes located on different chromosomes, and both enzymes are very similar in structure. They are homodimeric, heme containing, glycosylated proteins with two catalytic sites, but they differ substantially in their pattern of expression and biology. COX-1 is expressed constitutively in most tissues and at high levels in selected cells and tissues, including endothelium, monocytes, platelets, renal collecting tubules and seminal vesicles. COX-1 is thought to regulate a number of housekeeping activities involved in renal, gastrointestinal and platelet function. Inducible COX-2 is undetectable in most mammalian tissues but its expression can be induced rapidly (2-6h) in fibroblasts, endothelial cells, monocytes and ovarian follicles in response to growth factors, tumor promoters, hormones, bacterial endotoxin and cytokines. COX-2 is also expressed constitutively in specialized cell types or tissues where it plays specific functions in individual biological processes. These include reproduction, immunity, renal physiology, neurotransmission, bone resorption and pancreatic secretion. The COX-1 and COX-2 enzymes are important pharmacologically as targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, ibuprofen and the COX-2 inhibitors. Inhibition of cyclooxygenases with NSAIDs acutely reduces inflammation, pain and fever. Some methods to determine COX activity include measuring uptake of oxygen using an oxygraph, measuring the conversion of radioactive arachidonic acid, or measuring prostaglandins formed from PGH2 (such as determining PGH2 using immunoassays). These methods can be complex, time consuming and prone to interferences.
Supplier:
Spectrum Chemicals
Description:
Sodium Saccharin, Dihydrate, Powder, FCC is a white crystalline solid whose most common use is as an artificial sweetener. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
BeanTown Chemical
Description:
CAS: 1421-49-4; EC No: 215-823-2; MDL No: MFCD00008827; RTECS: DG6320000
Crystalline/Powder; Molecular Formula: C15H21O3; MW: 250.33
Melting Point: 206-209°
Supplier:
VWR International
Description:
Smooth-edged spreaders are excellent for spreading cultures and liquids without unwanted cutting, scraping, or gouging of agar during inoculation.
Supplier:
Spectrum Chemicals
Description:
Saccharin Sodium, Dihydrate, Powder, USP is a pharmaceutical grade substance whose most common use is as an artificial sweetener. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
AMBEED, INC
Description:
Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide xhydrate, Purity: 97%, CAS Number: 82385-42-0, Appearance: Colorless or White Powder or Crystals, Storage: Inert atmosphere, Room Temperature, Size: 25G
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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