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3,5-Dibromo-1H-pyrazole
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3,5-Dibromo-1H-pyrazole
Catalog Number:
(101796-002)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 008979-5G , MDL Number: MFCD00014503
Supplier:
Adipogen
Description:
R428 is a selective inhibitor of the receptor tyrosine kinase AXL. R428 blocks the catalytic and procancerous activities of AXL in vitro. 428 inhibits AXL at low nanomolar values and blocked AXL-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Reported IC(50) values are 11-14nM .
Supplier:
Adipogen
Description:
Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Might be used for binge-like ethanol drinking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
Catalog Number:
(101918-188)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059455-250MG , MDL Number: MFCD18374154
Supplier:
Adipogen
Description:
Tozasertib, or VX-680, is a potent and selective inhibitor of Aurora kinases, particularly Aurora A and B. In vitro, VX-680 blocks cell cycle progression and induces apoptosis in a wide range of human tumor types at low IC(50) values (i.e. 3.38nM for human BE-13 cells, and 14.34nM for NTERA cells). Moreover, VX680, also has very potent Ki values, with inhibition constants (Ki) of 0.6, 18, and 46nM for Aurora A, B, and C, respectively. VX-680 is also effective in vivo, being used in a Caki-1 xenograft model, VX-680 demonstrated a 75.7% (P < 0.001) decrease in Caki-1 xeno-graft tumor volume with no apparent alternation in animal body weight, peripheral blood counts, or other biological parameters.
Catalog Number:
(75831-174)
Supplier:
Restek
Description:
Contains: Acetonitrile (75-05-8); Acrylonitrile (107-13-1); Allyl chloride (3-chloropropene) (107-05-1); Benzene (71-43-2); Bromobenzene (108-86-1); Bromochloromethane (74-97-5); Bromodichloromethane (75-27-4); Bromoform (75-25-2); n-Butylbenzene (104-51-8); sec-Butylbenzene (135-98-8); tert-Butylbenzene (98-06-6); Carbon disulfide (75-15-0); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); 2-Chloroethanol (107-07-3); Chloroform (67-66-3); Chloroprene (2-chloro-1,3-butadiene) (126-99-8); 2-Chlorotoluene (95-49-8); 4-Chlorotoluene (106-43-4); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); Dibromomethane (74-95-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); cis-1,4-Dichloro-2-butene (1476-11-5); trans-1,4-Dichloro-2-butene (110-57-6); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); 1,3-Dichloropropane (142-28-9); 2,2-Dichloropropane (594-20-7); 1,1-Dichloropropene (563-58-6); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Diethyl ether (ethyl ether) (60-29-7); 1,4-Dioxane (123-91-1); Ethylbenzene (100-41-4); Ethyl methacrylate (97-63-2); Hexachloro-1,3-butadiene (87-68-3); Iodomethane (methyl iodide) (74-88-4); Isobutyl alcohol (2-methyl-1-propanol) (78-83-1); Isopropylbenzene (cumene) (98-82-8); 4-Isopropyl toluene (p-Cymene) (99-87-6); Methacrylonitrile (126-98-7); Methyl acrylate (96-33-3); Methyl methacrylate (80-62-6); Methylene chloride (dichloromethane) (75-09-2); Naphthalene (91-20-3); Nitrobenzene (98-95-3); 2-Nitropropane (79-46-9); Pentachloroethane (76-01-7); Propionitrile (107-12-0); n-Propylbenzene (103-65-1); Styrene (100-42-5); 1,1,1,2-Tetrachloroethane (630-20-6); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Tetrahydrofuran (109-99-9); Toluene (108-88-3); 1,2,3-Trichlorobenzene (87-61-6); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,2,3-Trichloropropane (96-18-4); 1,1,2-Trichlorotrifluoroethane (CFC-113) (76-13-1); 1,2,4-Trimethylbenzene (95-63-6); 1,3,5-Trimethylbenzene (108-67-8); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3)
Catalog Number:
(100504-052)
Supplier:
Electron Microscopy Sciences
Description:
(Glyoxaline)
C3H4N2 F.W. 68.08 Assay min 99.5% Imidazole is a lipid-enhancing buffer agent. When used with 4% osmium tetroxide solution in the post-fixation of tissue blocks, it produces a prominent electron-opaque staining of lipid droplets with no evidence of diffusion. Reference: Angermuller, S. Fahimi, H., Histochem. Journal 14, 823-35 (1982). 
Catalog Number:
(77626-670)
Supplier:
AMBEED, INC
Description:
Cholesterol acetate ≥95%
Supplier:
ALADDIN SCIENTIFIC
Description:
Atorvastatin Calcium, off white crystalline powder. It is a synthetic selective inhibitor of HMG-CoA reductase. It is insoluble in aqueous solution with pH below 4 and is freely soluble in methanol.It was used as standard in the method development and validation for simultaneous determination of Atorvastatin calcium and Ezetimibe in tablets using UV spectrophotometric, HPLC and HPTLC methods.
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Supplier:
Adipogen
Description:
Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
Supplier:
Enzo Life Sciences
Description:
A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.
Supplier:
TCI America
Description:
CAS Number: 73616-27-0
MDL Number: MFCD08063809 Molecular Formula: C5H9N3O Molecular Weight: 127.15 Purity/Analysis Method: >99.0% (GC) Form: Crystal Boiling point (°C): 140 Melting point (°C): 108
Catalog Number:
(RK30447)
Supplier:
Restek
Description:
Contains: 30042: 502.2 Calibration Mix #1 (gases); Bromomethane (methyl bromide) (74-83-9); Chloroethane (ethyl chloride) (75-00-3); Chloromethane (methyl chloride) (74-87-3); Dichlorodifluoromethane (CFC-12) (75-71-8); Trichlorofluoromethane (CFC-11) (75-69-4); Vinyl chloride (75-01-4);30431: 502.2 MegaMix Standard; Benzene (71-43-2); Bromobenzene (108-86-1); Bromochloromethane (74-97-5); Bromodichloromethane (75-27-4); Bromoform (75-25-2); n-Butylbenzene (104-51-8); sec-Butylbenzene (135-98-8); tert-Butylbenzene (98-06-6); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); 2-Chlorotoluene (95-49-8); 4-Chlorotoluene (106-43-4); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); Dibromomethane (74-95-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); 1,3-Dichloropropane (142-28-9); 2,2-Dichloropropane (594-20-7); 1,1-Dichloropropene (563-58-6); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Hexachloro-1,3-butadiene (hexachlorobutadiene) (87-68-3); Isopropylbenzene (cumene) (98-82-8); 4-Isopropyltoluene (p-cymene) (99-87-6); Methylene chloride (dichloromethane) (75-09-2); Naphthalene (91-20-3); n-Propylbenzene (103-65-1); Styrene (100-42-5); 1,1,1,2-Tetrachloroethane (630-20-6); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,3-Trichlorobenzene (87-61-6); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,2,3-Trichloropropane (96-18-4); 1,2,4-Trimethylbenzene (95-63-6); 1,3,5-Trimethylbenzene (108-67-8); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3);30300: 524 Calibration Mix #7A; Acetone (67-64-1); 2-Butanone (MEK) (78-93-3); 2-Hexanone (591-78-6); 4-Methyl-2-pentanone (MIBK) (108-10-1); Tetrahydrofuran (109-99-9);30304: 524 Calibration Mix #7B; Acrylonitrile (107-13-1); Allyl chloride (3-chloropropene) (107-05-1); Ethyl methacrylate (97-63-2); Methyl acrylate (96-33-3); Methyl methacrylate (80-62-6); Nitrobenzene (98-95-3); Pentachloroethane (76-01-7);30203: 524 Calibration Mix #8; Carbon disulfide (75-15-0); Chloroacetonitrile (107-14-2); 1-Chlorobutane (Butyl chloride) (109-69-3); trans-1,4-Dichloro-2-butene (110-57-6); 1,1-Dichloro-2-propanone (513-88-2); Diethyl ether (ethyl ether) (60-29-7); Hexachloroethane (67-72-1); Iodomethane (methyl iodide) (74-88-4); Methacrylonitrile (126-98-7); Methyl tert-butyl ether (MTBE) (1634-04-4); 2-Nitropropane (79-46-9); Propionitrile (107-12-0);30201: 524 Internal Standard/Surrogate Mix; 1-Bromo-4-fluorobenzene (BFB) (460-00-4); 1,2-Dichlorobenzene-d4 (2199-69-1); Fluorobenzene (462-06-6)
Supplier:
Matrix Scientific
Description:
2,3-Dibromo-3-phenylpropiophenone 95
Supplier:
AMBEED, INC
Description:
1,3-Dibromo-5-phenoxybenzene 98%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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