3-(4-Fluorophenyl)-5-methoxypyridine
Catalog Number:
(101819-340)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024984-500MG , MDL Number: MFCD09750918
Catalog Number:
(TCF0274-100MG)
Supplier:
TCI America
Description:
CAS Number: 1132-68-9
MDL Number: MFCD00063064 Molecular Formula: C9H10FNO2 Molecular Weight: 183.18 Purity/Analysis Method: >98.0% (T) Form: Crystal Specific rotation [a]20/D: -24 deg (C=1, H2O)
Supplier:
Thermo Scientific Chemicals
Description:
H-DL-Phe(4-F)-OH. Grade:98+, Melting Point ca 254*[degree]C. Boiling Point C:NA. C9H10FNO2. 51-65-0. HARMFUL
Supplier:
BeanTown Chemical
Description:
CAS: 1132-68-9; MDL No: MFCD00063064; RTECS: DW1765000
Solid; Molecular Formula: C9H10FNO2; MW: 183.18
Supplier:
TCI America
Description:
CAS Number: 446-22-0
MDL Number: MFCD00009893 Molecular Formula: C9H9FO Molecular Weight: 152.17 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Flash Point (°C): 79 Specific Gravity (20/20): 1.11
Supplier:
TCI America
Description:
CAS Number: 332-42-3
MDL Number: MFCD03844794 Molecular Formula: C8H8BrF Molecular Weight: 203.05 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 102 Flash Point (°C): 93 Specific Gravity (20/20): 1.45
Supplier:
AMBEED, INC
Description:
2',6'-Dichloro-3'-fluoroacetophenone, Purity: 98%, CAS Number: 290835-85-7, Appearance: Solid or liquid, Storage: Sealed in dry, Room Temperature, Size: 25g
Supplier:
AMBEED, INC
Description:
2-Chloro-4-fluorobenzyl alcohol, Purity: 98%, CAS Number: 208186-84-9, Appearance: White to yellow powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 25g
Supplier:
TCI America
Description:
CAS Number: 290835-85-7
MDL Number: MFCD02093760 Molecular Formula: C8H5Cl2FO Molecular Weight: 207.03 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 255 Specific Gravity (20/20): 1.40
Supplier:
Adipogen
Description:
AV-412 is a potent dual inhibitor of EGFR and ErbB2 tyrosine kinases, including the mutant EGFR(L858R,T790M), which is clinically resistant to the EGFR-specific kinase inhibitors erlotinib and gefitinib. In enzyme assays assay the compound inhibited the EGFR variants and ErbB2 in the nanomolar range with over 100-fold selectivity compared with other kinases, apart from ABL and FLT1, which were both moderately sensitive to the compound. In cells, AV-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively. It also inhibited epidermal growth factor (EGF)-dependent cell proliferation with an IC(50) of 100nM. Moreover, AV-412 abrogated EGFR signaling in the gefitinib-resistant H1975 cell line, which harbors a double mutation of L858R and T790M in EGFR. In animal studies using cancer xenograft models, AV-412 (30mg/kg) demonstrated complete inhibition of tumor growth of the A431 and BT-474 cell lines, which overexpress EGFR and ErbB2, respectively.
Catalog Number:
(76652-012)
Supplier:
AMBEED, INC
Description:
N-(4-Fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide, Purity: 97%, CAS Number: 1889279-16-6, Appearance: Solid, Storage: Sealed in dry, 2-8C, Size: 25MG
Catalog Number:
(77925-285)
Supplier:
AOB CHEM USA
Description:
6-CHLORO-4-METHOXYPYRIDINE-3-CARBAL 1G
Catalog Number:
(77892-470)
Supplier:
AMBEED, INC
Description:
2-CHLORO-5-METHOXYPYRIDIN-4-AMINE 1G
Catalog Number:
(ALB115758-100G)
Supplier:
ALADDIN SCIENTIFIC
Description:
5-BROMO-2-METHOXYPYRIDINE B115758-100G
Catalog Number:
(77884-608)
Supplier:
AMBEED, INC
Description:
2-BROMO-4-CHLORO-5-METHOXYPYRIDINE 1G
Catalog Number:
(77935-156)
Supplier:
AOB CHEM USA
Description:
(2-METHOXYPYRIDIN-3-YL)(PHENYL)METH 1G
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