3-(Carboxymethyl)benzoic+acid
Supplier:
Adipogen
Description:
Cell-permeable non-fluorescent reactive oxygen species (ROS) indicator. Passively diffuses across membranes where it is oxidized by peroxynitrite to rhodamine 123 which localizes in the mitochondria and exhibits green fluorescence (Ex/Em wavelengths of 500 and 536 nm). Used to investigate reactive oxygen intermediates produced by human and murine phagocytes, activated rat mast cells and cultured endothelial cells. In addition, it has been used together with Fura Red calcium indicator to simultaneously measure oxidative bursts and Ca2+ fluxes in monocytes and granulocytes. Dihydrorhodamine 123 has been shown to be a more sensitive probe than H2DCFDA for detecting granulocyte respiratory bursts.
Catalog Number:
(10108-336)
Supplier:
Prosci
Description:
UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
Supplier:
TCI America
Description:
CAS Number: 21245-02-3
MDL Number: MFCD00017526 Molecular Formula: C17H27NO2 Molecular Weight: 277.41 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 325 Flash Point (°C): 208 Specific Gravity (20/20): 1.00
Catalog Number:
(80053-226)
Supplier:
MilliporeSigma
Description:
Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 by peroxynitrite, but does not scavenge nitric oxide (NO).
Catalog Number:
(TCT0050-025G)
Supplier:
TCI America
Description:
CAS Number: 18472-87-2
MDL Number: MFCD00070627 Molecular Formula: C20H4Br4Cl4O5 Molecular Weight: 829.63 Purity/Analysis Method: >85.0% (E) Form: Crystal Color: Deep Yellow Red Lambda max.: 538 nm (0.02mol/L AcONH4 sol.)
Supplier:
Adipogen
Description:
LSD1 is a promising target for cancer therapy. Epigenetic control of histone methylation is frequently associated with oncogenesis and LSD1 is overexpressed in many types of cancer. siRNA knockdown of LSD1 has been shown to suppress growth of cancer cells. SP-2528 is a selective and reversible LSD1 inhibitor with an IC(50) of 10nM. SP-2528 demonstrates a high specificity for LSD1, with no effect on MAOi.
Catalog Number:
(77978-936)
Supplier:
LGC STANDARDS
Description:
Brombuterol Hydrochloride, TRC, LGC Standards
Supplier:
Genscript
Description:
To enable fast and efficient purification of antibody and epitope-tagged proteins, GenScript provides super paramagnetic magnetic beads. GenScript magnetic beads are coated with recombinant protein ligands that enable highly specific affinity binding to antibodies and epitope-tagged proteins.
Supplier:
Honeywell Research Chemicals
Description:
Karl Fischer titration is applied to multifarious substances. The nuances in sample properties influence the Karl Fischer titration differently. There are a number of ways to adjust the working conditions.
Catalog Number:
(76483-852)
Supplier:
AAT BIOQUEST INC
Description:
Chrysamine G is a lipophilic, bis-salicylic acid analog of Congo Red that displays both high (Kd = 200 nM; Bmax = 1.13 moles per mole of Ab40) and low (Kd = 38.77 µM; Bmax = 23.10 moles per mole of Ab40) affinity binding sites for beta-amyloid (Ab) fibrils.
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Supplier:
Ricca Chemical
Description:
Xylenol orange indicator 0.2% (w/v) in alcohol
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Supplier:
Bachem Americas
Description:
This sulfur-bridged cyclopeptide is a potent inhibitor of the binding of glycoprotein IIb/IIIa to fibrinogen with an IC₅₀ of 1.5 nM. Furthermore, it is a highly potent inhibitor of fibrinogen-mediated platelet aggregation (IC₅₀ = 0.15 µM). Its antithrombotic activity in vivo may render this compound useful in the treatment of arterial thromboembolic diseases.
Catalog Number:
(MSPP-CEB977GE)
Supplier:
CLOUD-CLONE CORP MS
Description:
This assay has high sensitivity and excellent specificity for detecting General species CML (Carboxymethyl Lysine). The assay range is from 61.7 to 5,000 ng/ml (Competitive kit) with a sensitivity of 25.9 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
Supplier:
Ricca Chemical
Description:
Xylenol orange indicator 0.1 % (w/v) in aqueous solution
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Supplier:
BeanTown Chemical
Description:
CAS: 98-88-4; EC No: 202-710-8; MDL No: MFCD00000653
UN No: UN1736; Haz Class: 8; Packing Group: II
Liquid; Molecular Formula: C7H5ClO; MW: 140.57
Melting Point: -1°; Boiling Point: 198°; Flash point: 72°C (162°F)
Density (g/mL): 1.211; Refractive Index: 1.553
Moisture Sensitive
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