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3-(Hydroxymethyl)-1-methyl-1H-indazole
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3-(Hydroxymethyl)-1-methyl-1H-indazole
Supplier:
AMBEED, INC
Description:
4-(Hydroxymethyl)-1H-benzimidazole 97%
Supplier:
AOB CHEM USA
Description:
4-Bromo-2-methyl-5-(trifluoromethyl)-2H-indazole ≥97%
Supplier:
AMBEED, INC
Description:
(S)-Morpholin-3-ylmethyl (4-((1-(3-fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)carbamate hydrochloride, Purity: 98+%, CAS Number: 873837-23-1, Appearance: White to off-white solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 50mg
Supplier:
AOB CHEM USA
Description:
6-Bromo-5-fluoro-3-iodo-2-methyl-2H-indazole ≥97%
Catalog Number:
(77142-792)
Supplier:
AMBEED, INC
Description:
2-Methyl-2H-indazol-5-ol, Purity: 97%, CAS Number: 1159511-41-7, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 deg C, Size: 250mg
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2-(Hydroxymethyl)indole 96%
Supplier:
AMBEED, INC
Description:
Benzydamine hydrochloride 98%
Catalog Number:
(101942-278)
Supplier:
Matrix Scientific
Description:
MF=C14H19Bn2O2 MW=258.13 Cas=1204580-79-9 1G
Supplier:
Matrix Scientific
Description:
MF=C8H9N3 MW=147.18 Cas=82013-51-2 MDL=MFCD09870044 5G
Catalog Number:
(77110-334)
Supplier:
AMBEED, INC
Description:
5-(Hydroxymethyl)pyridin-2(1H)-one, Purity: 98%, CAS Number: 109205-68-7, Appearance: White to yellow powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 100mg
Supplier:
AOB CHEM USA
Description:
Methyl 4-chloro-2-methyl-2H-indazole-5-carboxylate ≥97%
Supplier:
Matrix Scientific
Description:
1-(Hydroxymethyl)-1H-pyrazole-3-carboxylic acid
Supplier:
AMBEED, INC
Description:
2-Methyl-2H-indazole-5-carboxylic acid methyl ester 97%
Catalog Number:
(10300-588)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Supplier:
AMBEED, INC
Description:
5-Iodo-2-methyl-2H-indazole, Purity: 98%, CAS Number: 1150617-94-9, Appearance: Light yellow to yellow powder or crystals, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 10G
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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