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4-(Trifluoromethyl)benzenesulphonamide
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4-(Trifluoromethyl)benzenesulphonamide
Catalog Number:
(10300-356)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Catalog Number:
(10300-350)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Supplier:
Ricca Chemical
Description:
0.04% (w/v) Aqueous Solution. pH 3.0 (yellow) - 4.6 (blue). Plastic Container. 1L
Supplier:
TCI America
Description:
CAS Number: 34722-90-2
MDL Number: MFCD00077263 Molecular Formula: C27H28Br2O5S Molecular Weight: 646.37 Form: Crystal Color: Reddish Yellow
Supplier:
MP Biomedicals
Description:
Adenosine is a purine nucleoside comprising a molecule of adenine attached to a ribose sugar molecule moiety via a β-N9-glycosidic bond. It plays an important role in energy transfer. It is an endogenous purine nucleoside that modulates physiological process wherein cellular signaling by adenosine occurs through four known adenosine receptor subtypes (A1, A2A, A2B, and A3) Adenosine is an anti-inflammatory agent at the A(2A) receptor. Cardioprotective effects may relate to activation of A1 adenosine receptors.
Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD). Adenosine is used in topical treatment of foot wounds in diabetes mellitus and also used for the treatment or prevention of cardiac arrhythmias (irregular heartbeat).It is used to cause dilation of the blood vessels. Physical Appearance: White powder Optical Rotation: -68.0° to -72.0° (c=2, NaOH 1:20) Heavy Metals: ≤0.001% Loss on Drying: ≤0.5% Residue on Ignition: ≤0.1% Storage Temp. : -20 °C
Catalog Number:
(10300-354)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Catalog Number:
(EM1.01895.0010)
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00066901
Notes: Transition interval: pH 6.8 (yellow) to pH 8.2 (red)
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00148898
Notes: Transition interval: pH 3.8 (yellow) to pH 5.4 (blue)
Supplier:
BeanTown Chemical
Description:
CAS: 34725-61-6; EC No: 252-170-2; MDL No: MFCD00013793
Crystalline; Molecular Formula: C19H9Br4NaO5S; MW: 691.94
Catalog Number:
(TCB3195-1G)
Supplier:
TCI America
Description:
CAS Number: 34725-61-6
MDL Number: MFCD00013793 Molecular Formula: C19H10Br4O5S Molecular Weight: 691.94 Form: Crystal Color: Deep Green
Supplier:
AMBEED, INC
Description:
(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate, Purity: 95%, CAS Number: 23735-43-5, Appearance: Colorless to Yellow Liquid or Semi-Solid or solid, Storage: Inert atmosphere, 2-8 deg C, Size: 1g
Catalog Number:
(TS40326-0100)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Bromothymol blue sodium salt ACS
Catalog Number:
(BJ32768-50G)
Supplier:
Honeywell Research Chemicals
Description:
Bromophenol Blue sodium salt, Analytical, indicator, CAS Number: 34725-61-6, Synonym: 3aE raised to 2, 3aE raised to 2 aE raised to 2, 5aE raised to 2, 5aE raised to 2 aE raised to 2 -Tetrabromophenolsulfophthalein sodium salt, C19H9Br4NaO5S,Size: 50G
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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