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(R)-5-(Aminomethyl)pyrrolidin-2-one+hydrochloride
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(R)-5-(Aminomethyl)pyrrolidin-2-one+hydrochloride
Catalog Number:
(10390-018)
Supplier:
Bioss
Description:
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
Catalog Number:
(103410-874)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) - IHC-Prediluted from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) - IHC-Prediluted has been validated for the following applications: Immunohistochemistry-Paraffin.
Catalog Number:
(76085-348)
Supplier:
Bioss
Description:
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
Catalog Number:
(10390-034)
Supplier:
Bioss
Description:
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
Catalog Number:
(76116-260)
Supplier:
Bioss
Description:
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(10801-232)
Supplier:
Rockland Immunochemical
Description:
EPAC2, also known as Rap guanine nuclear exchange factor 4 and cAMPGEF-II, is belongs to a family of cyclic adenosine monophosphate (cAMP) binding proteins with guanine nucleotide exchange factor. Like the related protein EPAC1, EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, and inflammation. Recent evidence suggests that EPAC2 induces synapse remodeling and depression, with mutations in its gene being found in patients with autism.
Catalog Number:
(103410-896)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) [FITC] from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) [FITC] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(103410-890)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) [DyLight 650] from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) [DyLight 650] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(103410-892)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) [DyLight 680] from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) [DyLight 680] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Supplier:
Adipogen
Description:
Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon http://www.adipogen.com/ag-cr1-0154/adiporon.html . Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.
Catalog Number:
(89367-374)
Supplier:
Genetex
Description:
The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of G protein coupled receptors (GPCRs) for hormones, cytokines, and neurotransmitters. Cyclic nucleotides are important intracellular second messengers which play important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. One of the many phosphodiesterases that compartmentalized and hydrolyze cGMP in various tissues is phosphodiesterase type 5A. The cGMP is involved in nitric oxide signaling as well as cell signaling associated with natriuretic peptides and gulanylins. Some of the intracellular biding cites for the cGMP include cyclic nucleotide gated ion channels, cGMP dependent protein kinases, and cyclic GMP biding phosphodiesterases (cGB PDEs). The cGB PDEs include PDE2, PDE3, PDE5, PDE5 and PDE10; the members of these families contain various structural and functional motifs that are conserved. Most of these proteins contain dimmeric subunits that contain a highly conserved cGMP binding site and a phosphodiesterase catalytic site.
Catalog Number:
(103410-894)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) [DyLight 755] from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) [DyLight 755] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(103410-882)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) [DyLight 405] from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) [DyLight 405] has been validated for the following applications: Flow Cytometry, Immunohistochemistry-Paraffin.
Catalog Number:
(77244-996)
Supplier:
AMBEED, INC
Description:
2-Amino-9-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecin-2-yl)-3,9-dihydro-6H-purin-6-one, Purity: 98%, CAS: 849214-04-6, Appearance: White to off-white powder, Size: 1mg
Catalog Number:
(103410-898)
Supplier:
Novus Biologicals
Description:
The AMPD3 Antibody (AMPD3 / 901) [HRP] from Novus Biologicals is a mouse monoclonal antibody to AMPD3. This antibody reacts with human. The AMPD3 Antibody (AMPD3 / 901) [HRP] has been validated for the following applications: Immunohistochemistry-Paraffin.
Catalog Number:
(76292-930)
Supplier:
Cayman Chemical Company
Description:
Cyclic di-nucleotide phosphodiesterase (CdnP, also known as Rv2837c) is a soluble, stand-alone phosphodiesterase in regulating cyclic dinucleotide signaling during intracellular infections of <em>M. tuberculosis</em>{36095}. Studies have found that CdnP is capable of hydrolyzing cyclic di-adenosine monophosphate (c-di-AMP; Item No. 17753) into two AMPs as a strategy to avoid activation of the innate immune response of the host. <em>M. tuberculosis</em> infection leads to cytosolic release of c-di-AMP, which is recognized by stimulator of interferon genes (STING) and subsequently triggers type I interferon response. Other studies have shown that deletion or inhibition of CdnP attenuates the <em>M. tuberculosis</em> virulence both <em>in vitro</em> and <em>in vivo</em>.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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