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3-[(2-Bromo-4-ethylphenoxy)methyl]piperidine+hydrochloride
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3-[(2-Bromo-4-ethylphenoxy)methyl]piperidine+hydrochloride
Catalog Number:
(101935-432)
Supplier:
Matrix Scientific
Description:
MF=C16H24Brn3O2 MW=370.30 ,250Mg
Catalog Number:
(101844-312)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 037853-500MG , MDL Number: MFCD12027241
Supplier:
AMBEED, INC
Description:
(R)-tert-Butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate, Purity: 97% HPLC, CAS Number: 668273-75-4, Appearance: Solid, Storage: Sealed in dry, 2-8 C, Size: 5g
Catalog Number:
(101804-736)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 016442-500MG , MDL Number: MFCD06800735
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059661-1G , MDL Number: MFCD18803532
Supplier:
AMBEED, INC
Description:
4-Methyl-5-((4-((6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile, Purity: 97%, CAS Number: 1628317-18-9, Appearance: White to off white to yellow powder or crystals, Storage: Keep in dark place, Inert atmosphere, Store under -20 C, Size: 10mg
Catalog Number:
(101920-270)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 060576-500MG , MDL Number: MFCD16039372
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 048044-1G , MDL Number: MFCD00466217
Catalog Number:
(101934-822)
Supplier:
Matrix Scientific
Description:
MF=C13H26Cl3N5 MW=358.74 ,250Mg
Catalog Number:
(101934-360)
Supplier:
Matrix Scientific
Description:
2-Methyl-4-(3-Methyl-Piperidin-3-Yl)-Pyrimidine Dihydrochloride, MF=C11H19Cl2N3 MW=264.20 250Mg
Catalog Number:
(76871-144)
Supplier:
AMBEED, INC
Description:
Methyl 4-(3-(tert-butoxycarbonyl)ureido)piperidine-4-carboxylate 97%
Supplier:
Matrix Scientific
Description:
MF=C15H29N3O2 MW=283.42 CAS=1185064-24-7 MDL=MFCD09743693 5G
Supplier:
AMBEED, INC
Description:
6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid ≥99%
Catalog Number:
(101935-036)
Supplier:
Matrix Scientific
Description:
2-Chloro-6-(1-Methyl-Piperidin-2-Yl)-Pyrazine Dihydrochloride, MF=C10H16Cl3N3 MW=284.62 250Mg
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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