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2-(Difluoromethyl)pyrrolidine+hydrochloride
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2-(Difluoromethyl)pyrrolidine+hydrochloride
Supplier:
AMBEED, INC
Description:
6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid ≥99%
Supplier:
Matrix Scientific
Description:
MF=C13H24N2O3 MW=256.35 Cas=197727-57-4 1G
Catalog Number:
(77686-890)
Supplier:
AMBEED, INC
Description:
1-(tert-Butyl) 3-methyl (R)-piperidine-1,3-dicarboxylate ≥98%
Catalog Number:
(101929-958)
Supplier:
Matrix Scientific
Description:
MF=C14H26N2O4 MW=286.37 MDL=MFCD19103363 ,500Mg
Supplier:
AMBEED, INC
Description:
N-Methyl-N-(piperidin-4-yl)methanesulfonamide, Purity: 97%, CAS Number: 70724-74-2, Appearance: White to off-white to yellow powder or crystals, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 5g
Catalog Number:
(101939-678)
Supplier:
Matrix Scientific
Description:
MF=C20H28N2O6 MW=392.46 Cas=1221819-24-4 MDL=MFCD16039633 ,250Mg
Catalog Number:
(101830-910)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 030828-500MG , MDL Number: MFCD08569901
Catalog Number:
(77166-510)
Supplier:
AMBEED, INC
Description:
(4-(((1-(tert-butoxycarbonyl)piperidin-4-yl)oxy)methyl)phenyl)boronic acid, Purity: 95%, CAS Number: 1224449-13-1, Appearance: White to Yellow Solid, Storage: Inert atmosphere, 2-8 C, Size: 250mg
Catalog Number:
(77625-956)
Supplier:
AMBEED, INC
Description:
N-(1-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl)acrylamide ≥98%
Catalog Number:
(101815-378)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 023119-500MG , MDL Number: MFCD06246994
Supplier:
AMBEED, INC
Description:
1-Boc-isonipecotic acid methyl ester 98%
Catalog Number:
(101934-358)
Supplier:
Matrix Scientific
Description:
MF=C11H19Cl2N3O MW=280.20 250Mg
Supplier:
AMBEED, INC
Description:
1-((Tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-amine dihydrochloride, Purity: 97%, CAS Number: 1286274-47-2, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 100mg
Catalog Number:
(101933-856)
Supplier:
Matrix Scientific
Description:
MF=C13H18Cln3O2 MW=283.76 ,250Mg
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Catalog Number:
(101934-924)
Supplier:
Matrix Scientific
Description:
MF=C12H19Cln4O2S MW=318.83 ,250Mg
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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