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Catalog Number:
(76109-690)
Supplier:
Bioss
Description:
Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Catalog Number:
(76085-126)
Supplier:
Bioss
Description:
Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Atorvastatin (3S,5R) Isomer Calcium Salt (Atorvastatin USP Related Compound B), TLC Pharmaceutical Standards
Supplier:
AMBEED, INC
Description:
Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate hydrate, Purity: 95%, CAS Number: 402846-49-5, Appearance: White to off-white solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 100g
Catalog Number:
(76578-360)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat Glucose-6-Phosphate Dehydrogenase (G6PD) ELISA Kit, AFG Bioscience
Catalog Number:
(45001-130)
Supplier:
Corning
Description:
Phosphate Buffered Saline (PBS) is used to maintain a physiological pH and osmolarity, two key factors in tissue culture and molecular biology research
Catalog Number:
(10295-602)
Supplier:
Bioss
Description:
intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.
Catalog Number:
(75878-004)
Supplier:
BIOASSAY SYSTEMS
Description:
For quantitative determination of phosphate concentrations.
Supplier:
KPL
Description:
10X Phosphate-buffered Saline (PBS) is ideal for use in sample preparation and as a wash buffer in general immunoassay applications.
Catalog Number:
(76741-144)
Supplier:
ANTIBODIES.COM LLC
Description:
Human Sphingosine-1-phosphate ELISA kit is a competitive Enzyme-Linked Immunosorbent Assay (cELISA) designed for the <i>in vitro</i> quantitative determination of human Sphingosine-1-phosphate in serum, plasma, tissue homogenates, and other biological fluids.
Catalog Number:
(10801-754)
Supplier:
Rockland Immunochemical
Description:
Anti-Glycerol-3-Phosphate Dehydrogenase recognizes the enzyme glycerol-3-phosphate dehydrogenase, a major component of lipid biosynthesis. Glyercol-3-phosphate dehydrogenase catalyzes the reduction of dihydroxyacetone phosphate (DHAP) to glycerol-3-phosphate. In addition, it assists in maintaining the redox potential across the inner mitochondrial membrane in glycloysis. Glycerol-3-phosphate dehydrogenase can be found in the cytosol and the inner mitochondrial membrane.
Anti-Glycerol-3-Phosphate Dehydrogenase is ideal for investigators interested in metabolism, cancer, and cardiovascular diseases.
Catalog Number:
(10342-914)
Supplier:
Bioss
Description:
Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).
Catalog Number:
(76483-128)
Supplier:
AAT BIOQUEST INC
Description:
EGTA (1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid) is a water-soluble and cell-impermeable calcium chelator.
Catalog Number:
(76483-050)
Supplier:
AAT BIOQUEST INC
Description:
Calcium measurement is critical for numerous biological investigations.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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