3-[1,1\\\\\\\\\\\\\\\'-Biphenyl]-4-ylacrylic+acid
Catalog Number:
(10283-154)
Supplier:
Bioss
Description:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-∫, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
Catalog Number:
(103270-854)
Supplier:
Novus Biologicals
Description:
The SMAP Antibody from Novus Biologicals is a rabbit polyclonal antibody to SMAP. This antibody reacts with human. The SMAP Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number:
(80055-494)
Supplier:
MilliporeSigma
Description:
A derivative of papaverine that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells
Catalog Number:
(10207-930)
Supplier:
Boster Biological Technology
Description:
Mouse IgG monoclonal antibody for MAP Kinase, Activated (Diphosphorylated ERK-1&2), mitogen-activated protein kinase 1; mitogen-activated protein kinase 3 (MAPK1; MAPK3 ) detection. Tested with WB, IHC-P, ICC in Human;mouse;rat;yeast. No cross reactivity with other proteins.
Catalog Number:
(10748-198)
Supplier:
Prosci
Description:
STAT1 alpha Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-alpha , IFN-beta, IFN-gamma; and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1).
Supplier:
BeanTown Chemical
Description:
CAS: 126330-77-6
Solid; Molecular Formula: C8H13NO4; MW: 187.19
Melting Point: 121-122°; Boiling Point: 319°; Flash point: 147°C (297°F)
Density (g/mL): 1.185
Catalog Number:
(103360-930)
Supplier:
Novus Biologicals
Description:
The RGS11 Antibody from Novus Biologicals is a rabbit polyclonal antibody to RGS11. This antibody reacts with human, mouse, rat. The RGS11 Antibody has been validated for the following applications: Western Blot.
Catalog Number:
(75933-198)
Supplier:
Rockland Immunochemical
Description:
Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.
Supplier:
TCI America
Description:
N,N,N',N'-Tetraphenylbenzidine, Purity: >99.0%(GC), Cas number: 15546-43-7, Molecular Formula: C36H28N2, Molecular Weight: 488.63, Synonyms: 4,4'-Bis(diphenylamino)biphenyl, TPB (purified by sublimation), Size: 1G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 046875-5G , MDL Number: MFCD02683049
Supplier:
Restek
Description:
Pinnacle® DB guard cartridges protect HPLC columns as well as remove particulate contaminants and highly adsorptive compounds from samples, prolonging analytical column life.
Supplier:
TCI America
Description:
CAS Number: 15546-43-7
MDL Number: MFCD00228123 Molecular Formula: C36H28N2 Molecular Weight: 488.63 Purity/Analysis Method: >98.0% (GC) Form: Crystal Color: White Melting point (°C): 233 Lambda max.: 354 nm (CHCl3)
Catalog Number:
(75929-628)
Supplier:
Rockland Immunochemical
Description:
Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
Catalog Number:
(10277-062)
Supplier:
Bioss
Description:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
Catalog Number:
(103275-398)
Supplier:
Novus Biologicals
Description:
The ARL11 Antibody from Novus Biologicals is a rabbit polyclonal antibody to ARL11. This antibody reacts with human. The ARL11 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
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