3-Hydroxy-2\'-methoxy-2-naphthanilide
Supplier:
Spectrum Chemicals
Description:
EUGENOL, USP, is used in perfumeries, flavorings, essential oils and in medicine as a local antiseptic and anesthetic. Eugenol can be combined with zinc oxide to form a material – known as zinc oxide eugenol – which has restorative and prosthodontic applications in dentistry. The USP grade indicates it is graded suitable for personal care, cosmetic and pharmaceutical applications. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Storage temperature - LIGHT SENSITIVE: Keep tightly closed in light-resistant containers.
Supplier:
Adipogen
Description:
Reference standard.
Supplier:
BeanTown Chemical
Description:
CAS: 130-95-0; EC No: 205-003-2; MDL No: MFCD00198096; RTECS: VA6020000
Crystalline; Molecular Formula: C20H24N2O2; MW: 324.42
Melting Point: 173-175°
Optical Rotation: [α]20/D -126±5°, c = 1% in chloroform
Light Sensitive
Catalog Number:
(IC0210116625)
Supplier:
MP Biomedicals
Description:
β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of two oxidation-reduction coenzymes: nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). The nicotinamide portion of the coenzyme transfers hydrogens by alternating between oxidized quaternary nitrogen and a reduced tertiary nitrogen. NADP is an essential coenzyme for glucose-6-phosphate dehydrogenase which catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconic acid. This reaction initiates metabolism of glucose by a pathway other than the citric acid cycle. This route is known as the hexose phosphate shunt or phosphogluconate pathway. Other enzymes which utilize NADP as a coenzyme are: Alcohol dehydrogenase:NADP dependent; Aromatic ADH:NADP dependent; Ferredoxin-NADP reductase; L-Fucose dehydrogenase; Gabase; Galactose-1-phosphate uridyl transferase; Glucose dehydrogenase; L-Glutamic dehydrogenase; Glycerol dehydrogenase:NADP specific; Isocitric dehydrogenase; Malic enzymes; 5,10-Methylenetetrahydrofolate dehydrogenase; 6-Phosphogluconate dehydrogenase and Succinic semialdehyde dehydrogenase.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,6-Di-tert-butyl-4-methoxyphenol 97%
Catalog Number:
(TCA0232-100ML)
Supplier:
TCI America
Description:
CAS Number: 97-53-0
MDL Number: MFCD00008654 Molecular Formula: C10H12O2 Molecular Weight: 164.20 Purity/Analysis Method: >99.0% (GC) Form: Clear Liquid Boiling point (°C): 254 Melting point (°C): -9 Flash Point (°C): 127 Specific Gravity (20/20): 1.07
Supplier:
MP Biomedicals
Description:
Flavin Adenine Dinucleotide is a prosthetic group of certain oxidases.
Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex. Store at -0 °C.
Catalog Number:
(EM8.02304.0025)
Supplier:
BeanTown Chemical
Description:
CAS: 90-05-1; EC No: 201-964-7; MDL No: MFCD00002185; RTECS: SL7525000
Crystalline; Molecular Formula: C7H8O2; MW: 124.14
Melting Point: 26-29°; Boiling Point: 205°; Flash point: 82°C (179°F)
Density (g/mL): 1.129; Refractive Index: 1.543
Air Sensitive, Light Sensitive
Supplier:
Spectrum Chemicals
Description:
4-Methoxyphenol is a white, waxy solid with a phenolic, caramel odor. Also known as Mequinol and MeHQ, it is soluble in benzene, acetone, and alcohol. It is used as an antioxidant to inhibit the radical polymerization of monomers, a phenol in dermatology, and in dyestuffs. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for consumption.
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Catalog Number:
(200001-490)
Supplier:
Spectrum Chemicals
Description:
Quinine, Anhydrous is an antiarrhythmic agent.
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Supplier:
AMBEED, INC
Description:
4,4'-Dimethoxybenzhydrol 98%
Supplier:
Adipogen
Description:
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells with IC(50) values of 20 and 45nM, respectively. SAR131675 dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC(50) of about 20nM. SAR131675 was found to be highly selective for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. However, it was moderately active on VEGFR-2 with a VEGFR-3/VEGFR-2 ratio of about 10. SAR131675 had no antiproliferative activity on a panel of 30 tumors and primary cells, further showing its high specificity and indicating that SAR131675 is not a cytotoxic or cytostatic agent.
Supplier:
Adipogen
Description:
Antibiotic. Shows antiviral, antifungal and antitumor properties. Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis. Potent reversible inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), leading to depletion of GMP and interruption of the de novo synthesis of purine nucleotides necessary for B and T lymphocyte proliferation. Inhibits the type II IMPDH isoform (IMPDH-2) 5-fold more potently compared to type I isoform. Inhibits RNA and DNA synthesis. Inducible nitric oxide synthase (iNOS/NOS II) inhibitor. Apoptosis and necrosis inducer. Novel type of inhibitor against RNA guanylyltransferases. Inhibits TNF-alpha-stimulated MAPK/NF-kappaB and ROS generation.
Supplier:
Adipogen
Description:
It is known that phenol and p-cresol are promoters of skin tumors and also urinary excretion of phenol and p-cresol is increased by exposure to benzene, which has hemopoietic toxicity, and toluene, respectively. Therefore, the determination of phenol and p-cresol is important in clinical chemistry and toxicology. Because phenol and p-cresol are present in urine as sulfate or glucuronide conjugates, they are hydrolyzed enzymatically or with acid, followed by distillation or extraction with organic solvent prior to measurement by GC or HPLC. However, these GC and HPLC methods require relatively large sample volumes (more than 1 ml) because of their insufficient sensitivities for measuring small amounts of phenol and p-cresol. In the general, the application of fluorescent labeling techniques to HPLC result in a sensitive and selective method. Some acyl chlorides are known to react with phenolic hydroxy group to form esters. It is known that 4-(N-phthalimidinyl)benzensulfonyl chloride Phisyl-Cl7, having sulfonyl chloride, reacted with phenol to give the corresponding highly fluorescent sulfonyl ester. The sensitivity of Physil-Cl was compared with Dansyl-Cl and DPS-Cl, which are analogous to Physil-Cl as fluorescent labeling reagents having sulfonyl chloride group. The labeling reaction of phenol with Dansyl-Cl and DPS-Cl were carried out according to the method of Ruiter et al.5 and the peaks were detected at the each fluorescence maxima wavelength (Ex350nm a Em550nm for Dansyl-Cl, and Ex320nm a Em386nm for DPS-Cl). Peak height of Phisyl derivative was higher about 85-and 7,3-fold than thosse of Dansyl derivative and DPS derivative, respectively. Among these three reagents, Phisyl-Cl was the most sensitive.
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