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(±)-2,2-Difluoro-1-methylcyclopropanecarboxylic+acid
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(±)-2,2-Difluoro-1-methylcyclopropanecarboxylic+acid
Supplier:
Biotium
Description:
GelRedâ„¢ and GelGreenâ„¢ are a new generation of fluorescent nucleic acid gel stains designed to replace the highly toxic ethidium bromide (EtBr)
Supplier:
Biotium
Description:
CellBriteâ„¢ Fix dyes are fluorogenic membrane dyes that covalently stain the plasma membrane in live cells. They are unique among membrane stains in which they can withstand both fixation and detergent permeabilisation.
Supplier:
Biotium
Description:
This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Supplier:
Biotium
Description:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
Cytokeratin 6 Monoclonal antibody, Clone: LHK6, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: A synthetic peptide of 11 amino acids from C-terminus of human keratin 6, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
beta-2 microglobulin Monoclonal antibody, Clone: BBM.1, Host: Mouse, Species reactivity: Human, Non-human primates, Isotype: IgG2b, K, Conjugate: biotin, Immunogen: MOLT-4 human T cell line, Synonyms: B2M, Application: IF, Size: 500 uL
Supplier:
Biotium
Description:
Cytokeratin 18 Monoclonal antibody, Clone: DA7, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Human breast cancer PMC 42 cells, Synonyms: K18, Application: IF, IHC, WB, FC, Size: 500 uL
Supplier:
Biotium
Description:
This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
Supplier:
Biotium
Description:
P21 / WAF1, Monoclonal antibody, Clone: DCS-60.2, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF640R, Immunogen: Recombinant full-length human CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2), Application: IF, IHC, Size: 100uL
Supplier:
Biotium
Description:
CD32 Monoclonal antibody, Clone: 7.3, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: K562 and FcgRII L cellsUnigene 352642, Application: Immunofluorescence, Flow cytometry, Size: 500 uL
Supplier:
Biotium
Description:
CD38 Monoclonal antibody, Clone: AT2, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: biotin, Immunogen: human T cell line CCRF-CEM, Synonyms: Acute Lymphoblastic Leukemia Cells Antigen, Application: IF, FC, Size: 500 uL
Supplier:
Biotium
Description:
This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
Supplier:
Biotium
Description:
Cytokeratin 19 Monoclonal antibody, Clone: A53-B/A2 + BA17, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF405S, Immunogen: Human breast cancer MCF-7 cells, Synonyms: k19, k1cs, krt19, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Supplier:
Biotium
Description:
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Supplier:
Biotium
Description:
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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