4,4\'-(Hexafluoroisopropylidene)dianiline
Catalog Number:
(76109-136)
Supplier:
Bioss
Description:
BRP44 is a 127 amino acid protein belonging to the UPF0041 family. The gene that encodes BRP44 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Supplier:
Sper Scientific
Description:
Monitor visible light levels anywhere with a fast, stable, and accurate response
Catalog Number:
(TCN0096-100G)
Supplier:
TCI America
Description:
CAS Number: 3264-82-2
MDL Number: MFCD00000024 Molecular Formula: C10H14NiO4 Molecular Weight: 256.91 Purity/Analysis Method: >98.0% (T) Form: Crystal
Catalog Number:
(470012-820)
Supplier:
NADA SCIENTIFIC LTD.
Description:
With this generator, students have the power of electricity in the palm of their hands.
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Catalog Number:
(10782-368)
Supplier:
Biosensis
Description:
FUNCTION: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. May be involved in copper homeostasis/oxidative stress through copper ion reduction. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. FUNCTION: Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. Rat and mouse beta-amyloid peptides bind only weakly transient metals and have little reducing activity due to substitutions of transient metal chelating residues. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation (By similarity). FUNCTION: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis. SUBUNIT: Binds, via its C-terminus, to the PID domain of several cytoplasmic proteins, including APBB family members, the APBA family, MAPK8IP1, SHC1, Numb and Dab1. Binding to Dab1 inhibits its serine phosphorylation. Also interacts with GPCR-like protein BPP, FPRL1, APPBP1, IB1, KNS2 (via its TPR domains), APPBP2 (via BaSS) and DDB1. In vitro, it binds MAPT via the MT-binding domains. Associates with microtubules in the presence of ATP and in a kinesin-dependent manner. Interacts, through a C-terminal domain, with GNAO1. Amyloid beta-42 binds CHRNA7 in hippocampal neurons. Beta-amyloid associates with HADH2. TISSUE SPECIFICITY: different isoforms in different tissues: kidney. brain. liver. hippocampus, substania nigra pars compacta and cerebellum. In the cerebellum, all the isoforms are abundantly expressed in Purkinje cells.
Catalog Number:
(AAAB21710-18)
Catalog Number:
(101912-200)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 057055-50G , MDL Number: MFCD00008541
Catalog Number:
(AAAA12640-14)
Catalog Number:
(101927-950)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064572-500MG , MDL Number: MFCD00004248
Supplier:
AMBEED, INC
Description:
meso-Tetra(4-carboxyphenyl)porphine 97%
Catalog Number:
(TCD0803-025G)
Supplier:
TCI America
Description:
CAS Number: 621-01-2
MDL Number: MFCD00008541 Molecular Formula: C15H16N2S Molecular Weight: 256.37 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 179
Catalog Number:
(TCP0100-025G)
Supplier:
TCI America
Description:
CAS Number: 143-74-8
MDL Number: MFCD00003552 Molecular Formula: C19H14O5S Molecular Weight: 354.38 Form: Crystal Color: Deep Yellow Red
Catalog Number:
(100504-184)
Supplier:
Electron Microscopy Sciences
Description:
A standard indicator for preparing buffers, pH range 6.4 to 8.2.
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Catalog Number:
(BJ32661-25G)
Supplier:
Honeywell Research Chemicals
Description:
Phenol Red, Analytical, indicator, ACS Reagent, CAS Number: 143-74-8, Synonym: Phenolsulfonphthalein, Molar Mass: 354.38 g/mol, Reagent, ACS Indicator, Size: 25G
Catalog Number:
(102989-434)
Supplier:
Adipogen
Description:
Building block for synthesis. Reagent used for electrophilic phenylation, e.g. of malonates and dithiocarboxylates.
Catalog Number:
(TCB1680-025G)
Supplier:
TCI America
Description:
CAS Number: 2479-46-1
MDL Number: MFCD00039154 Molecular Formula: C18H16N2O2 Molecular Weight: 292.34 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 116 Flash Point (°C): 300
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