4-(Cbz-amino)piperidine+Hydrochloride
Catalog Number:
(102845-544)
Supplier:
Matrix Scientific
Description:
tert-Butyl-3-{[3-(trifluoromethyl)phenyl]amino}piperidine-1-carboxylate ≥95%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059585-1G , MDL Number: MFCD18651782
Catalog Number:
(101924-218)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062613-500MG , MDL Number: MFCD08457385
Catalog Number:
(101924-220)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062614-500MG , MDL Number: MFCD08457384
Catalog Number:
(101836-240)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 033721-500MG , MDL Number: MFCD00776902
Catalog Number:
(101931-152)
Supplier:
Matrix Scientific
Description:
MF=C10H15N5O2 MW=237.26 MDL=MFCD11083009 ,500Mg
Catalog Number:
(101846-790)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039084-500MG , MDL Number: MFCD12027588
Catalog Number:
(101929-396)
Supplier:
Matrix Scientific
Description:
MF=C21H25N3O5S MW=431.51 MDL=MFCD08747037 ,500Mg
Catalog Number:
(101847-028)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039205-500MG , MDL Number: MFCD12027708
Catalog Number:
(101846-956)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039168-500MG , MDL Number: MFCD12027672
Supplier:
Adipogen
Description:
AT7519 is a potent inhibitor of several CDK family members. AT7519 showed potent antiproliferative activity (40-940nM) in a panel of human tumor cell lines, and the mechanism of action was shown here to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT7519 caused cell cycle arrest followed by apoptosis in human tumor cells and inhibited tumor growth in human tumor xenograft models. Tumor regression was observed following twice daily dosing of AT7519 in the HCT116 and HT29 colon cancer xenograft models. Also it has been shown that the biological effects are linked to inhibition of CDKs in vivo and that AT7519 induces tumor cell apoptosis in these xenograft models. Moreover, AT7519 has an attractive biological profile and is well tolerated and effective making it a more plausible candidate for clinical development than previously available CDK inhibitors. In in vitro kinase assays AT7519 showed nanomolar levels of activity from <lt/>10 to 2400 for cyclins; only one other non-cyclin related kinase was inhibited at levels below 10µM (GSK3beta, 89nM), all others tested had IC(50)'s of greater than 10,000nM.
Catalog Number:
(101929-408)
Supplier:
Matrix Scientific
Description:
MF=C17H23N3O5S MW=381.45 MDL=MFCD08743694 ,500Mg
Supplier:
AMBEED, INC
Description:
tert-Butyl 4-(4-amino-2-fluorophenyl)piperidine-1-carboxylate, Purity: 97%, CAS Number: 188975-15-7, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 1G
Supplier:
AMBEED, INC
Description:
1-(5-Aminopyridin-2-yl)piperidin-4-ol, Purity: 98%, CAS Number: 476342-37-7, Appearance: Yellow to brown powder or crystals, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 250mg
Supplier:
AMBEED, INC
Description:
3-((3R,4R)-4-Methyl-3-(methyl(6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 98%
Catalog Number:
(101849-322)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 040343-500MG , MDL Number: MFCD12028204
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