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4-(Pyrimidin-5-yl)benzoic+acid
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4-(Pyrimidin-5-yl)benzoic+acid
Supplier:
AMBEED, INC
Description:
1-(Pyrimidin-2-yl)piperidin-4-ol 95%
Catalog Number:
(101934-362)
Supplier:
Matrix Scientific
Description:
(6-Piperidin-4-Yl-Pyrazin-2-Yl)-Pyrimidin-2-Yl-Amine Hydrochloride MF=C13H17Cln6 MW=292.77, 250Mg
Supplier:
AMBEED, INC
Description:
2-(Pyrimidin-5-yl)benzaldehyde, Purity: 95%, CAS Number: 640769-71-7, Appearance: White to Yellow or Gray Solid, Storage: Inert atmosphere, Room Temperature, Size: 250MG
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Catalog Number:
(77686-122)
Supplier:
AMBEED, INC
Description:
2-(Piperazin-1-yl)pyrimidine hydrochloride ≥97%
Supplier:
AMBEED, INC
Description:
2-(Piperidin-4-yl)pyrimidine hydrochloride 95%
Supplier:
AMBEED, INC
Description:
4-(Pyridin-4-yl)pyrimidine, Purity: 95%, CAS Number: 53345-78-1, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1G
Supplier:
Matrix Scientific
Description:
MF=C9H6BRN3 MW=236.08 CAS=942189-65-3 MDL=MFCD09999083 1G
Supplier:
Matrix Scientific
Description:
MF=C11H8N2O MW=184.20 CAS=640769-71-7 MDL=MFCD02684096 10G
Supplier:
Adipogen
Description:
Fluorescent probe. Long wavelength red labeling derivative for proteins. Can be used as a reversible inhibitor of the erythrocyte calcium pump as well as an effective phosphorescent probe in measurement of rotational diffusion of proteins and in fluorescence energy transfer (FRET) studies. EITC tagged molecules may be used together with fluorescein-5′-isothiocyanate (FITC) tagged molecules in fluoresce resonance energy transfer (FRET) based assays. Spectral properties: Abs/Em = 520/544 nm
Supplier:
AMBEED, INC
Description:
6-(Pyridin-3-yl)pyrimidin-4-amine, Purity: 97%, CAS Number: 1192814-34-8, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 250mg
Catalog Number:
(102834-074)
Supplier:
Matrix Scientific
Description:
3-{[4-(Trifluoromethyl)pyrimidin-2-yl]oxy}aniline ≥97%
Catalog Number:
(102840-668)
Supplier:
Matrix Scientific
Description:
3-(Pyrimidin-2-yl)bromobenzene ≥97%
Catalog Number:
(102840-666)
Supplier:
Matrix Scientific
Description:
4-(Pyrimidin-2-yl)bromobenzene ≥97%
Catalog Number:
(102841-164)
Supplier:
Matrix Scientific
Description:
2-Chloro-4-(pyrrolidin-1-yl)pyrimidine ≥97%
Supplier:
AMBEED, INC
Description:
(2-(Trifluoromethyl)pyrimidin-5-yl)methanol, Purity: 98%, CAS Number: 608515-90-8, Appearance: White to Yellow Solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 100mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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