4-(Trifluoromethyl)benzenesulphonamide
Catalog Number:
(77150-242)
Supplier:
AMBEED, INC
Description:
2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide, Purity: 95%, CAS Number: 1261295-10-6, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100mg
Supplier:
AMBEED, INC
Description:
3-Bromo-N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzenesulfonamide, Purity: 97%, CAS Number: 2828445-43-6, Appearance: Solid, Storage: Sealed in dry, 2-8C, Size: 5G
Catalog Number:
(76996-010)
Supplier:
AMBEED, INC
Description:
4-tert-Butyl-N-(6-chloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide, Purity: 97%, CAS number: 150727-06-3, Appearance: White to off-white solid, Storage: Inert atmosphere, 2-8C, Size: 5G
Catalog Number:
(TS46560-0050)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Sulfamethazine sodium salt
Supplier:
Adipogen
Description:
GSK2126458 is an orally available selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzymesand MTOR1/2 complexes. GSK2126458 can inhibit PI3K-alpha (p85alpha/p110alpha) with IC(50) of 0.04nM. GSK2126458 has Ki values in the picomolar range for each of the class I PI3K isoforms and MTOR1/2 complexes. GSK2126458 has potent in vitro and in vivo growth-inhibitory effects on cancer cells. In comparison with other clinical PI3K inhibitors, GSK2126458 is around 100-fold more potent than BEZ235 (6nM). GSK2126458 also a low picomolar inhibitor of the common activating mutants of p110R ( E542K, E545K, and H1047R ) with Ki of 0.008nM, 0.008nM and 0.009nM in human cancer. In mechanistic cellular assays, GSK2126458 caused a significant reduction in the levels of pAKT-S473 with remarkable potency. Consistent with its activity against both PI3K R and mTOR, GSK2126458 also inhibits phosphorylation of AKT-T308 and p70S6K at low nanomolar concentrations. GSK2126458 induces a G1 cell cycle arrest and inhibits cell proliferation in a large panel of cell lines, including T47D and BT474 breast cancer lines.
Supplier:
AMBEED, INC
Description:
3-Amino-N,N-dimethylbenzenesulfonamide, Purity: 97%, CAS Number: 6274-18-6, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 5g
Catalog Number:
(IC15670980)
Supplier:
MP Biomedicals
Description:
Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.
Supplier:
TCI America
Description:
CAS Number: 1981-58-4
MDL Number: MFCD00068333 Molecular Formula: C12H14N4O2S Molecular Weight: 300.31 Purity/Analysis Method: >97.0% (HPLC,N) Form: Crystal Color: White Storage Temperature: 0-10°C
Catalog Number:
(102835-408)
Supplier:
Matrix Scientific
Description:
4-(Trifluoromethyl)nicotinaldehyde 95
Catalog Number:
(AAAL19554-03)
Supplier:
APOLLO SCIENTIFIC
Description:
3-(Trifluoromethyl)benzylamine 97%
Supplier:
Thermo Scientific Chemicals
Description:
2-[4-(Trifluoromethyl)phenyl]ethylamine, 98%
Supplier:
APOLLO SCIENTIFIC
Description:
(S)-2-(Trifluoromethyl)pyrrolidine 97%
Supplier:
AMBEED, INC
Description:
4'-(Trifluoromethyl)acetanilide 98%
Supplier:
AOB CHEM USA
Description:
4-Trifluoromethyl thioanisole ≥97%
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