Methyl+2-bromo-2-(3-methoxyphenyl)acetate
Catalog Number:
(75788-760)
Supplier:
Prosci
Description:
At least 23 different variants of IFN- alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN- alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN- alpha subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Catalog Number:
(77440-486)
Supplier:
Bioss
Description:
The regulation of the intracellular concentration of calcium is important for proper maintenance of voltage-gated ion channels which control muscle and nerve function. Calcium homeostasis is regulated by a variety of proteins. CHERP (calcium homeostasis endoplasmic reticulum protein), also known as SRA1, DAN16 or SCAF6, is a 916 amino acid protein that localizes to the cytoplasm and the endoplasmic reticulum (ER). Expressed in pancreas, brain, lung, placenta, liver, kidney, heart and skeletal muscle, CHERP is involved in maintaining calcium homeostasis and plays a role in cell growth and proliferation. CHERP contains one G-patch domain, one RPR domain and one SURP motif and is expressed as two isoforms due to alternative splicing events.
Catalog Number:
(TCC0398-100G)
Supplier:
TCI America
Description:
CAS Number: 60-27-5
MDL Number: MFCD00059730 Molecular Formula: C4H7N3O Molecular Weight: 113.12 Purity/Analysis Method: >99.0% (HPLC,T) Form: Crystal Melting point (°C): 255 Flash Point (°C): 290
Supplier:
Shenandoah Biotechnology
Description:
Interferon-alpha 2b (IFN-α2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α2b. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α2b variant differs from IFN-α2a by one amino acid.
Supplier:
Adipogen
Description:
Widely used fluorophore well-known for preparing fluorogenic 7-Amido-4-methylcoumarin (AMC) substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
Catalog Number:
(89361-020)
Supplier:
Genetex
Description:
Corticotropin (ACTH), synthesized by the anterior pituitary gland, stimulates the adrenal cortex. Human ACTH has a molecular weight of 4,541 and contains 39 amino acids . It has structural similarities to melanotropin (melanocyte-stimulating hormone; MSH). Human beta-melanotropin has 22 amino acid residues and a molecular weight of 2,661. Work on the structure of the ACTH gene by restriction enzyme techniques showed that 6 hormones are derived from one gene: ACTH, lipotropin, alpha-MSH, beta-MSH, endorphin, and one other. Thus, extensive amino acid differences between these hormones were not adequate evidence for their being distinct. ACTH and beta-lipotropin (beta-LPH) are derived from a large precursor peptide. Each of these hormones is known to include smaller peptides having distinct biologic activities: alpha-melanotropin (alpha-MSH) and corticotropin-like intermediate lobe peptide (CLIP) are formed from ACTH; gamma-LPH and beta-endorphin are peptide components of beta-LPH. Beta-MSH is contained within gamma-LPH. The precursor peptide was called proopiomelanocortin (POMC).
Supplier:
AMBEED, INC
Description:
1-(2-Amino-3-hydroxyphenyl)ethanone, Purity: 95%, CAS Number: 4502-10-7, Appearance: Form: Crystal - Powder/Colour: Pale yellow - Deep yellow, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 5g
Supplier:
Anaspec Inc
Description:
5(6)-TAMRA is the mixture of two carboxy tetramethylrhodamine (TMR) isomers. It is used to modify amino and hydroxy groups using EDC-mediated couplings when there are difficulties in using 5(6)-TAMRA, SE. TAMRA is one of the most popular fluorophores used in various bioconjugations.
Catalog Number:
(TCF0534-1G)
Supplier:
TCI America
Description:
CAS Number: 2341-22-2
Molecular Formula: C9H12FN3O5 Molecular Weight: 261.21 Purity/Analysis Method: >97.0% (T) Form: Crystal Melting point (°C): 193 Specific rotation [a]20/D: 55 deg (C=1, MeOH)
Catalog Number:
(76109-720)
Supplier:
Bioss
Description:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
Catalog Number:
(10665-752)
Supplier:
Bioss
Description:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
Catalog Number:
(103010-370)
Supplier:
Anaspec Inc
Description:
Biotin, SE is amino-reactive biotinylating reagent for peptides and proteins; it has a better avidin-binding affinity than biotin. Biotin, SE (d-Biotin-N-hydroxysuccinimide ester) contains a five-carbon spacer arm that reduces steric hindrance associated with binding four biotinylated molecules per one avidin and results in enhanced detection sensitivity.
Supplier:
PeproTech, Inc.
Description:
Members of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related, and share a high degree of amino acid sequence identity (e.g. Shh and Ihh are 93% identical). The biologically active form of each Hh molecule is obtained by autocatalytic cleavage of their precursor proteins, and each corresponds to approximately one half of the N-terminal portion of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can be substituted for one another in experimental systems. Recombinant Murine Sonic Hedgehog (Shh) is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the naturally occurring, chemically modified Cys residue.
Catalog Number:
(10281-794)
Supplier:
Bioss
Description:
DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Catalog Number:
(10081-290)
Supplier:
Proteintech
Description:
The MAOB gene encodes a 520-amino acid protein with a molecular mass of 58.8 kD and shows 70% amino acid identity to MAOA. MAOA and MAOB are present in the outer mitochondrial membrane in the central nervous system and peripheral tissues.A comparison of highly purified human placental MAOA and human liver MAOB revealed that the A form of the enzyme is larger by 2 kDa and only one potential N-glycosylation site exists in each protein, with each site in a different relevant position .
Catalog Number:
(103008-616)
Supplier:
Anaspec Inc
Description:
This peptide is histone H3 amino acid residues 1 to 21. It is asymmetrically dimethylated at arginine 8 with both methyl groups added to one nitrogen of the guanidinium group, and contains a C-terminal biotinylated lysine.
Sequence:ARTKQTA-R(Me2a)-KSTGGKAPRKQLA-K(Biotin)-NH2 MW:2636.1 Da % peak area by HPLC:95 Storage condition:-20° C
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