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2,3-Dimethylisonicotinic acid hydrochloride
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2,3-Dimethylisonicotinic acid hydrochloride
Supplier:
PeproTech, Inc.
Description:
Complement 5a (C5a) is an enzymatically generated glycoprotein belonging to the anaphylatoxin family of structurally and functionally related proteins. Generated upon the activation of the complement system, C5a, together with C4a, C3a, and the membrane attack complex (C5b-9), functions as a central player in host defense by inducing smooth muscle cell contraction, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes through cell degranulation. In addition to acting as a direct mediator of localized inflammatory response, C5a also initiates both the synthesis and release of IL-8 from monocytes and bronchial epithelial cells, stimulates the proliferation of neurons and hepatocytes, and functions as a potent chemoattractant. Where C5a deficiency, a rare defect of the complement pathway caused by the mutation of the C5a gene, is associated with susceptibility to severe infections, excessive C5a activation has been linked to liver fibrosis, sepsis, adult respiratory distress syndrome, rheumatoid arthritis, Alzheimer’s disease, and ischemic heart disease. Human C5a shares 60% and 54% sequence identity to mouse and rat C5a, respectively. The human C5 gene encodes a 1,676 amino acid glycoprotein that is comprised of a disulfide-linked C5 alpha and a C5 beta chain, the former of which contains the active, 74 amino acid C5a anaphylatoxin chain. Recombinant Human C5a is an 8.28 kDa glycoprotein containing the 74 amino acid residues of the C5a anaphylatoxin chain.
Supplier:
Prosci
Description:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
Supplier:
MP Biomedicals
Description:
Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is crosslinked by three disulfide bridges. Aprotinin is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.
Catalog Number:
(77685-242)
Supplier:
AMBEED, INC
Description:
3-Boc-aminoethylazetidine ≥96%
Supplier:
Bachem Americas
Description:
Sequence: H-β-Chloro-Ala-OH · HCl
Catalog Number:
(80056-726)
Supplier:
MilliporeSigma
Description:
(L-5-HTP). Off-white solid. PROTECT FROM LIGHT. Serotonin precursor. Purity: >= 95% by HPLC. Soluble in acidic solutions and H2O. RTECS YN7110000, CAS 4350-09-8, M.W. 220.2. WARNING! Harmful. LD50 of <= 2000 mg/kg.
Catalog Number:
(10113-406)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Immunogen: ZIC3 antibody was raised against a 14 amino acid synthetic peptide near the internal region of ZIC3 (aa 205-218), Tested Applications: ELISA
Catalog Number:
(10113-340)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Immunogen: DSP antibody was raised against a 13 amino acid synthetic peptide near the internal region of DSP (aa 1546-1558), Tested Applications: ELISA
Catalog Number:
(10113-172)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species Reactivity: Human, Immunogen: SERPINB11 antibody was raised against a 13 amino acid synthetic peptide near the internal region of SERPINB11, Tested Applications: ELISA
Catalog Number:
(10113-462)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species Reactivity: Human, Immunogen: KCNIP3 antibody was raised against a 11 amino acid peptide near the internal region of KCNIP3, Tested Applications: ELISA, WB
Catalog Number:
(10115-924)
Supplier:
Prosci
Description:
Polyclonal antibody DORFIN Host: Goat Target Species: human immunogen: DORFIN antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of DORFIN. Application: ELISA
Catalog Number:
(10115-998)
Supplier:
Prosci
Description:
Polyclonal antibody GNRPX Host: Goat Target Species: human immunogen: GNRPX antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of GNRPX. Application: ELISA
Catalog Number:
(10115-250)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat; Target Species: Human; Immunogen: UBN1 antibody was raised against a 15 amino acid peptide near the internal region of UBN1; Applications: ELISA,Western blotting
Catalog Number:
(10112-106)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species: Human, Immunogen: SORBS1 antibody was raised against a 14 amino acid synthetic peptide near the internal region of SORBS1, Application: ELISA
Catalog Number:
(10112-946)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species: Human, Immunogen: TIP30 antibody was raised against a 14 amino acid synthetic peptide near the N-Terminus of TIP30, Application: ELISA, WB
Catalog Number:
(10113-842)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Immunogen: Akap12 antibody was raised against a amino acid synthetic peptide near the internal region of Akap12 (mouse), Tested Applications: ELISA, WB
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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