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2-Methoxyphenyl+isothiocyanate
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2-Methoxyphenyl+isothiocyanate
Catalog Number:
(10072-844)
Supplier:
Prosci
Description:
IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042425-1G , MDL Number: MFCD00236863
Catalog Number:
(101822-904)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 026804-500MG , MDL Number: MFCD10687265
Catalog Number:
(101836-728)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 033973-500MG , MDL Number: MFCD03617826
Catalog Number:
(101924-590)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062808-500MG , MDL Number: MFCD00159595
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 024051-100G , MDL Number: MFCD00002488
Catalog Number:
(101794-608)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 008405-500MG , MDL Number: MFCD02737984
Catalog Number:
(101843-202)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 037360-500MG , MDL Number: MFCD09376386
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 049607-2.5G , MDL Number: MFCD13560009
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050188-2.5G , MDL Number: MFCD13560589
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050246-2.5G , MDL Number: MFCD13560647
Catalog Number:
(10109-588)
Supplier:
Prosci
Description:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 is the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
Supplier:
BeanTown Chemical
Description:
CAS: 20694-39-7; MDL No: MFCD00149789
UN No: UN2724; Haz Class: 5.1; Packing Group: III
Crystalline; Linear Formula: Mn(NO3)2·4H2O; MW: 251.01
Melting Point: 26°
Hygroscopic
Catalog Number:
(AA15122-36)
Supplier:
Thermo Scientific Chemicals
Description:
UN1564,Powder,WARNING: Causes GI injury, skin and eye irritation,100g,500g,KEEP AWAY FROM FOOD,
Catalog Number:
(89350-872)
Supplier:
Genetex
Description:
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa ""signal"" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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