Polysorbate+80
Supplier:
MP Biomedicals
Description:
Tryptic Soy Broth is a highly nutritive and very versatile medium used for the cultivation of fastidious and non-fastidious microorganisms and used frequently in many procedures of diagnostic research or microbiology.
Catalog Number:
(75841-674)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.
Catalog Number:
(76008-844)
Supplier:
Prosci
Description:
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).
Catalog Number:
(75842-534)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-β, which down-regulates the Treg cells action. 
Catalog Number:
(75842-652)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The MF23 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression. Mutations of Foxp3 result in the “scurfy†mice phenotype. It is reported that the MF23 antibody recognizes an epitope between 1-87 amino acids in the N-terminal domain of mouse Foxp3.
Catalog Number:
(75842-778)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Catalog Number:
(75843-172)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.
We recommend that this antibody be incubated for at least 45 minutes at 4°C for optimal staining.
Catalog Number:
(75843-216)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
Catalog Number:
(75844-412)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.
Catalog Number:
(75841-696)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Catalog Number:
(75841-918)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor α (IL-2R α, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor β chain (CD122) and the common γ chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
Catalog Number:
(75841-914)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor α (IL-2R α, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor β chain (CD122) and the common γ chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
Catalog Number:
(75841-648)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.
Catalog Number:
(75843-602)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The D7 monoclonal antibody specifically reacts with mouse Ly-6A/E (Sca-1), a 18 kDa GPI-linked surface protein. It is expressed on multipotent hematopoietic stem cells (HSC) and subsets of B and T cells and involved in B and T cell lymphocyte responses. Splenocytes from Ly-6.2 strains exhibit a larger number of D7-positive cells than those from the Ly-6.1 strains.
Catalog Number:
(75841-766)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The Sa2-8 monoclonal antibody specifically reacts with mouse CD14, a cell surface anchored glycoprotein that is primarily expressed on macrophages and is secreted in certain conditions. CD14 associates with LPS and LBP to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The Sa2-8 antibody exhibits a weak antagonistic activate in relation to TNF alpha production and NF-kappa B activation.
Catalog Number:
(75843-032)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.
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