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4-Bromo-5-(trifluoromethyl)-1H-indazole
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4-Bromo-5-(trifluoromethyl)-1H-indazole
Supplier:
AMBEED, INC
Description:
tert-Butyl-3-bromopyrazolo[3,4-b]pyridine-1-carboxylate 95%
Catalog Number:
(101821-848)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 026217-100MG , MDL Number: MFCD08741534
Supplier:
AMBEED, INC
Description:
2-Methyl-6-(trifluoromethyl)pyrimidin-4-ol 97%
Supplier:
TCI America
Description:
CAS Number: 6941-75-9
MDL Number: MFCD00466049 Molecular Formula: C8H4BrNO2 Molecular Weight: 226.03 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 235
Supplier:
Matrix Scientific
Description:
MF=C13H16BRNO2 MW=298.19 CAS=261732-38-1 MDL=MFCD08059280 5G
Supplier:
Adipogen
Description:
Inhibitor of pan-Trk activity (IC(50) = 8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC(50) = 11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC(50) = 42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC(50) = 1 and 0.5µM) and Ba/F3-Tel-KDR and wt-Ba/F3 cells (IC(50) = 3.0 and 5.6µM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.).
Supplier:
TCI America
Description:
CAS Number: 52488-36-5
MDL Number: MFCD00671502 Molecular Formula: C8H6BrN Molecular Weight: 196.05 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 96 Flash Point (°C): 110 Specific Gravity (20/20): 1.58
Catalog Number:
(AAAL11189-03)
Supplier:
Thermo Scientific Chemicals
Description:
3-Acetoxy-1-acetyl-5-bromoindole. Grade:98+, Melting Point C122-125*. Boiling Point C:NA. C12H10BrNO3. 33588-54-4. KEEP COLD
Supplier:
TCI America
Description:
CAS Number: 51417-51-7
MDL Number: MFCD00799492 Molecular Formula: C8H6BrN Molecular Weight: 196.05 Purity/Analysis Method: >97.0% (GC) Form: Crystal Melting point (°C): 46 Flash Point (°C): 113
Supplier:
Matrix Scientific
Description:
MF=C9H6Brno MW=224.06 Cas=98600-34-1 MDL=MFCD05864695 25G
Supplier:
MP Biomedicals
Description:
Storage: Store at -20 °C. Store Desiccated. Store Under Nitrogen. Protect from light.
5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside, commonly known as X−Gal, is a histochemical substrate for β−galactosidase. 5-Bromo-4-Chloro-3-Indolyl-β-D-Galactopyranoside is used as indigogenic substrate for β-galactosidase, for detection of β-galactosidase-positive clones, and the identification of lac and bacterial colonies or phage plaques. It is the substrate of choice for blue-white selection of recombinant bacterial colonies with the lac+ genotype. X−Gal is cleaved by β−galactosidase to yield an insoluble blue precipitate. X−Gal is particularly useful in molecular biology applications to detect the activity of β−galactosidase which is frequently used as a reporter gene. In cloning, X−Gal is used to detect insertion of foreign DNA into the lacZ region of plasmid DNA using α-complementation which is based on vectors such as the pUC and the M13mp series that carry a fragment of the β-galactosidase gene encoding an α-fragment of β-galactosidase.
Supplier:
BeanTown Chemical
Description:
CAS: 25233-30-1; MDL No: MFCD00241446
Powder; Linear Formula: [-C6H5NH-]n; MW ≈15,000
Melting Point: <gt/>200° (decomposes)
Catalog Number:
(76003-202)
Supplier:
Enzo Life Sciences
Description:
Potent and selective ATP non-competitive inhibitor of MEK1/2
Supplier:
AMBEED, INC
Description:
5-Bromoisoindoline-1,3-dione, Purity: 98%, CAS Number: 6941-75-9, Appearance: Form: Crystal - Powder, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 25g
Supplier:
AMBEED, INC
Description:
5-Bromoindan-2-ol, Purity: 97%, CAS Number: 862135-61-3, Appearance: White to pale-yellow to gray powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 250MG
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